Results 51 to 60 of about 96,912 (310)

Immunomodulation Part IV: Glutamine

, 2006
SEPSIS CONTINUES TO BE A significant cause of neonatal morbidity and mortality. Researchers have been exploring various modalities, including immunomodulation, as adjuncts to antibiotics to enhance the neonatal immune system.
Susan Givens Bell
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda

npj Vaccines
Vaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in
Jacent Nassuuna, Joas Sterk, Bridgious Walusimbi, Agnes Natukunda, Ronald Nkangi, Rebecca Amongin, Ludoviko Zirimenya, Emily L. Webb, Alison M. Elliott, Gyaviira Nkurunungi   +9 more
doaj   +1 more source

Antileishmanial Activity of Flavones-Rich Fraction From Arrabidaea chica Verlot (Bignoniaceae)

Frontiers in Pharmacology, 2021
Acknowledging the need of identifying new compounds for the treatment of leishmaniasis, this study aimed to evaluate, from in vitro trials, the activity of flavones from Arrabidaea chica against L. amazonensis.
João Victor Silva-Silva, Carla Junqueira Moragas-Tellis, Maria do Socorro dos Santos Chagas, Paulo Victor Ramos de Souza, Paulo Victor Ramos de Souza, Celeste da Silva Freitas de Souza, Daiana de Jesus Hardoim, Noemi Nosomi Taniwaki, Davyson de Lima Moreira, Maria Dutra Behrens, Kátia da Silva Calabrese, Fernando Almeida-Souza, Fernando Almeida-Souza   +12 more
doaj   +1 more source

Leptin as an immunomodulator

Molecular Aspects of Medicine, 2012
Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with neuroendocrine and immune functions. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. Initially described as an antiobesity hormone, leptin has subsequently been shown also to influence basal ...
Procaccini C, Jirillo E, Matarese G
openaire   +6 more sources

Immunomodulators for Asthma [PDF]

Allergy, Asthma and Immunology Research, 2010
New information regarding the molecular mechanisms of allergic disorders has led to a variety of novel therapeutic approaches. This article briefly reviews the pathogenesis of asthma and allergic diseases, discusses the rationale behind using immunomodulators in these diseases; and examines the therapeutic effects of immunomodulators on allergic ...
Dimov, Vesselin V, Casale, Thomas B
openaire   +2 more sources

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Immunomodulation—a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system

Frontiers in Immunology, 2023
In recent years, there has been a tremendous development of biotechnological, pharmacological, and medical techniques which can be implemented in the functional modulation of the immune system components.
Martyna Strzelec, Jan Detka, Patrycja Mieszczak, Małgorzata Katarzyna Sobocińska, Marcin Majka   +4 more
doaj   +1 more source

Percutaneous Ablation-Induced Immunomodulation in Hepatocellular Carcinoma

, 2020
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related deaths worldwide and its incidence is rising. Percutaneous locoregional therapies, such as radiofrequency ablation and microwave ablation, are widely used as curative ...
Lucile Dumolard, Zuzana Macek Jilkova, Gael Roth, Ghelfi, Julien, Decaens, Thomas, Roth, Gael, Macek Jilkova, Zuzana, Julien Ghelfi, Thomas Decaens, Dumolard, Lucile   +9 more
core   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source