Results 71 to 80 of about 109,666 (292)

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Elevated Pentraxin 3 in Obese Adipose Tissue Promotes Adipogenic Differentiation by Activating Neuropeptide Y Signaling

Frontiers in Immunology, 2018
Obesity is accompanied by chronic systemic inflammation characterized by macrophage infiltration of obese tissues, an elevated plasma level of inflammatory substances, and excessive accumulation of lipids.
Min-Kyung Shin, Min-Kyung Shin, Bongkun Choi, Bongkun Choi, Eun-Young Kim, Eun-Young Kim, Ji-Eun Park, Ji-Eun Park, Eui Seung Hwang, Hyang Ju Lee, Hyang Ju Lee, Min Kyung Kim, Min Kyung Kim, Ji-Eun Kim, Seong Who Kim, Seong Who Kim, Eun-Ju Chang, Eun-Ju Chang   +17 more
doaj   +1 more source

Immunomodulation by Ayurveda: A New Frontier in Modern Health Care [PDF]

Immunomodulation is described as regulation and modulation of immunity that might be achieved by reducing or enhancing the immune response depending on the intended result.
Archit Kumar, Brahm Dutt Sharma, Nisha Ojha   +2 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Pulmonary inflammatory response and immunomodulation to multiple trauma and hemorrhagic shock in pigs_blot images

, 2022
Raw western blot images for the original research manuscript "Pulmonary inflammatory response and immunomodulation to multiple trauma and hemorrhagic shock in pigs" 
Martin Sassen (13953359), Bernd T. Schmeck (8786771), Marc-Alexander Oestreich (8769359), Hans-Helge Müller (158349), Thorsten Steinfeldt (9870476), Hinnerk Wulf (745052), Kerstin Seidel (385253), Wilhelm Bertrams (3172785)   +7 more
core   +1 more source

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Rural-urban differences in oral typhoid vaccine responses in Uganda: contribution of Schistosoma mansoni

npj Vaccines
Vaccine immunogenicity varies across populations, yet drivers remain unclear. We compared systemic (plasma) and mucosal (coprological) antibody responses to the oral typhoid vaccine Ty21a, quantified by ELISA, among Ugandan adolescents from urban and ...
Bridgious Walusimbi, Agnes Natukunda, Rebecca Amongin, Victoria Heyraud, Claire Baine, Jacent Nassuuna, Emily L. Webb, Alison M. Elliott, Gyaviira Nkurunungi   +8 more
doaj   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Immunomodulation by serine phospholipids.

, 1992
Immunomodulation by serine ...
Ponzin D., CASELLI, Elisabetta, Bruni A., Bellini F., Monastra G.   +4 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source