Results 1 to 10 of about 630,798 (317)

Concept of natural genome reconstruction. Part 5. Analysis of changes in the lifespan of old animals after reinfusion of bone marrow cells derived from old animals and treated with hDNA^gr in combination with recombinant human angiogenin [PDF]

Вавиловский журнал генетики и селекции
Two series of tests were performed, on mice and rats, to assess the lifespan of old animals reinfused with bone marrow cells from old animals treated with fragmented human DNA (hDNAgr), recombinant human angiogenin, and both preparations together ...
V. S. Ruzanova, L. U. Grivtsova, S. G. Oshikhmina, А. S. Proskurina, G. S. Ritter, E. V. Dolgova, S. S. Kirikovich, E. V. Levites, Y. R. Efremov, T. D. Dubatolova, M. I. Meschaninova, A. L. Mamaev, O. S. Taranov, S. V. Sidorov, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, A. S. Bryukhovetskiy, S. S. Bogachev   +19 more
doaj   +2 more sources

Impact of glucocorticoids on short-term and long-term outcomes in patients with relapsed/refractory multiple myeloma treated with CAR-T therapy

Frontiers in Immunology, 2022
BackgroundGlucocorticoids (GCs) are often used to treat cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The effects of GCs on the efficacy of CAR-T cell treatment in relapsed/refractory multiple myeloma
Xue Wang, Xue Wang, Xue Wang, Yuekun Qi, Yuekun Qi, Yuekun Qi, Hujun Li, Hujun Li, Hujun Li, Fengan Liu, Jiang Cao, Jiang Cao, Jiang Cao, Wei Chen, Wei Chen, Wei Chen, Ying Wang, Ying Wang, Ying Wang, Kunming Qi, Kunming Qi, Kunming Qi, Zhiling Yan, Zhiling Yan, Zhiling Yan, Feng Zhu, Feng Zhu, Feng Zhu, Zhenyu Li, Zhenyu Li, Zhenyu Li, Hai Cheng, Hai Cheng, Hai Cheng, Kailin Xu, Kailin Xu, Kailin Xu   +36 more
doaj   +1 more source

A combination of pre-infusion serum ferritin, CRP and IL-6 predicts outcome in relapsed/refractory multiple myeloma patients treated with CAR-T cells

Frontiers in Immunology, 2023
BackgroundChimeric antigen receptor - T (CAR-T) cell therapy has shown remarkable efficacy in patients with relapsed/refractory multiple myeloma (R/R MM).
Yang Liu, Yang Liu, Yang Liu, Xingxing Jie, Xingxing Jie, Xingxing Jie, Li Nian, Li Nian, Li Nian, Ying Wang, Ying Wang, Ying Wang, Congyue Wang, Congyue Wang, Congyue Wang, Jin Ma, Jin Ma, Jin Ma, Jingjing Jiang, Jingjing Jiang, Jingjing Jiang, Qingyun Wu, Qingyun Wu, Qingyun Wu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wei Chen, Wei Chen, Wei Chen, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Ming Shi, Hai Cheng, Hai Cheng, Hai Cheng, Feng Zhu, Feng Zhu, Feng Zhu, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Chong Chen, Chong Chen, Chong Chen, Kailin Xu, Kailin Xu, Kailin Xu, Zhenyu Li, Zhenyu Li, Zhenyu Li   +57 more
doaj   +1 more source

EPC infusion ameliorates acute graft-versus-host disease-related endothelial injury after allogeneic bone marrow transplantation

Frontiers in Immunology, 2022
IntroductionGraft-versus-host disease (GVHD) damages vascular endothelium. Endothelial progenitor cell (EPC) can differentiate to endothelial cell and promote angiogenesis, but its role in endothelial damage in GVHD is unclear.MethodsIn this study, we ...
Weiwei Wang, Weiwei Wang, Weiwei Wang, Yali Ye, Yali Ye, Yali Ye, Yuwei Du, Yuwei Du, Yuwei Du, Zhengqing Xu, Zhengqing Xu, Zhengqing Xu, Ke Yuan, Ke Yuan, Ke Yuan, Yizhou Wang, Yizhou Wang, Yizhou Wang, Seyram Yao Adzraku, Seyram Yao Adzraku, Seyram Yao Adzraku, Yue Li, Yue Li, Yue Li, Kailin Xu, Kailin Xu, Kailin Xu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wen Ju, Wen Ju, Wen Ju, Lingyu Zeng, Lingyu Zeng, Lingyu Zeng   +35 more
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Immunotherapies targeting GPRC5D in relapsed or refractory multiple myeloma: latest updates from 2022 ASH Annual Meeting

Journal of Hematology & Oncology, 2023
B cell maturation antigen (BCMA)-targeted immunotherapy has shown unprecedented results in the treatment of relapsed or refractory (R/R) multiple myeloma (MM).
Jieyun Xia, Zhenyu Li, Kailin Xu
doaj   +1 more source

Bone marrow SSEA1+ cells support the myocardium in cardiac pressure overload. [PDF]

PLoS ONE, 2013
Stage specific embryonic antigen 1+ (SSEA1+) cells have been described as the most primitive mesenchymal progenitor cell in the bone marrow. Cardiac injury mobilizes SSEA1+ cells into the peripheral blood but their in vivo function has not been ...
Amanda Finan, Nikolai Sopko, Feng Dong, Ben Turturice, Matthew Kiedrowski, Marc S Penn   +5 more
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Incorporation of bone marrow cells in pancreatic pseudoislets improves posttransplant vascularization and endocrine function. [PDF]

PLoS ONE, 2013
Failure of revascularization is known to be the major reason for the poor outcome of pancreatic islet transplantation. In this study, we analyzed whether pseudoislets composed of islet cells and bone marrow cells can improve vascularization and function ...
Christine Wittig, Matthias W Laschke, Claudia Scheuer, Michael D Menger   +3 more
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Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN [PDF]

, 2004
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the ...
Walz, A., Kolbow, K., Chaubal, S., Pauli, C., Andratschke, M., Wollenberg, Barbara   +5 more
core   +1 more source

Enzyme‐Cleaved Bone Marrow Transplantation Improves the Engraftment of Bone Marrow Mesenchymal Stem Cells

JBMR Plus, 2023
Mesenchymal stem cell (MSC) therapy is a promising approach to curing bone diseases and disorders. In treating genetic bone disorders, MSC therapy is local or systemic transplantation of isolated and in vitro proliferated MSC rather than bone marrow ...
Hotaka Kawai, May Wathone Oo, Kiyofumi Takabatake, Ikue Tosa, Yamin Soe, Htoo Shwe Eain, Sho Sanou, Shigeko Fushimi, Shintaro Sukegawa, Keisuke Nakano, Takarada Takeshi, Hitoshi Nagatsuka   +11 more
doaj   +1 more source

Cytokines inducing bone marrow SCA+ cells migration into pancreatic islet and conversion into insulin-positive cells in vivo. [PDF]

PLoS ONE, 2009
We hypothesize that specific bone marrow lineages and cytokine treatment may facilitate bone marrow migration into islets, leading to a conversion into insulin producing cells in vivo.
LuGuang Luo, John Z Q Luo, Fang Xiong, Mehrdad Abedi, Deborah Greer   +4 more
doaj   +1 more source