JBMR Plus, 2023 Mesenchymal stem cell (MSC) therapy is a promising approach to curing bone diseases and disorders. In treating genetic bone disorders, MSC therapy is local or systemic transplantation of isolated and in vitro proliferated MSC rather than bone marrow ...
Hotaka Kawai +11 more
doaj +1 more source
Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]
, 2004 Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Dimmeler, S +8 more
core +1 more source
Generation of osteoinductive grafts by three-dimensional perfusion culture of human bone marrow cells into porous ceramic scaffolds [PDF]
, 2005 The main aims of this thesis were (i) to identify and develop a system that could be reproducibly used to streamline manufacture of osteoinductive grafts based on human bone marrow stromal cells (BMSC) in the context of regenerative medicine, (ii) to ...
Braccini, Alessandra
core +1 more source
Prospective isolation of human bone marrow stromal cell subsets: a comparative study between Stro-1-, CD146- and CD105-enriched populations [PDF]
, 2014 Stro-1 has proved an efficacious marker for enrichment of skeletal stem and progenitor cells although isolated populations remain heterogeneous, exhibiting variable colony-forming efficiency and osteogenic differentiation potential. The emerging findings
Greenhough, Joanna +7 more
core +1 more source
Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia [PDF]
, 2010 Background: Increasing evidence suggests that cell therapy improves functional recovery in experimental models of stroke and myocardial infarction.
Wolf-Rüdiger Schäbitz +13 more
core +1 more source
Bone marrow mesenchymal stem cell niches and regenerative medicine [PDF]
, 2010 Mesenchymal progenitors are a powerful tool in regenerative medicine, but suffer from a rapid loss of differentiation potential during in vitro expansion.
Di Maggio, Nunzia
core +1 more source
In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]
, 2009 We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I +32 more
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Supersensitive PSA-Monitored neoadjuvant hormone treatment of clinically localized prostate cancer: Effects on positive margins, tumor detection and epithelial cells in bone marrow [PDF]
, 1998 Objective: The present study was done to investigate the effects of supersensitive PSA-controlled inductive treatment on positive margins, detection of tumor and epithelial cells in bone marrow of 101 patients with untreated and clinically localized ...
Köllermann, J. +7 more
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Splenocytes seed bone marrow of myeloablated mice: implication for atherosclerosis. [PDF]
PLoS ONE, 2015 Extramedullary hematopoiesis has been shown to contribute to the pathogenesis of a variety of diseases including cardiovascular diseases. In this process, the spleen is seeded with mobilized bone marrow cells that augment its hematopoietic ability. It is
Lai Wang +10 more
doaj +1 more source
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]
, 2002 Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Dimmeler, S +12 more
core +1 more source