Results 41 to 50 of about 5,678,862 (294)

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]

, 2009
We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I, Arnaud Scherberich, Montjovent, MO, Scherberich, A, Scherberich, Arnaud, Lee Ann Applegate, Montjovent, Marc-Olivier, Marc-Olivier Montjovent, Scaletta, Corinne, Dominique P. Pioletti, Bocelli-Tyndall, Chiara, Martin, Ivan, Applegate, LA, Laurent-Applegate, Lee, Bocelli-Tyndall, C., Pioletti, DP, Scherberich, A., Silke Mark, Montjovent, M.O., Scaletta, C, Pioletti, Dominique P., Mark, Silke, Mark, S., Bocelli-Tyndall, C, Applegate, Lee Ann, Mark, S, Pioletti, D.P., Corinne Scaletta, Scaletta, C., Ivan Martin, Martin, I., Applegate, L.A., Chiara Bocelli-Tyndall   +32 more
core   +2 more sources

Construction and validation of a nutritional status (CONUT)-based nomogram for predicting prolonged hematological toxicity in relapsed/refractory multiple myeloma after CAR-T cell therapy

Frontiers in Nutrition
Background aimChimeric antigen receptor (CAR)-T cell therapy is highly effective for relapsed/refractory multiple myeloma (R/R MM). Prolonged hematological toxicity (PHT) is a significant adverse event that adversely affects patient outcomes; however ...
Peng Xu, Peng Xu, Peng Xu, Xin-Ying Duan, Xin-Ying Duan, Xin-Ying Duan, Qi-Wen Feng, Qi-Wen Feng, Qi-Wen Feng, Ya-Wen Wang, Ya-Wen Wang, Ya-Wen Wang, Yang Liu, Yang Liu, Yang Liu, Huan-Xin Zhang, Huan-Xin Zhang, Huan-Xin Zhang, Kun-Ming Qi, Kun-Ming Qi, Kun-Ming Qi, Zhen-Yu Li, Zhen-Yu Li, Zhen-Yu Li, Qing-Yun Wu, Qing-Yun Wu, Qing-Yun Wu   +26 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

In vitro and in vivo characterization of murine bone marrow stromal stem cells: self renewal, differentiation, tumorigenic potential [PDF]

, 2009
The use of adult stem cells for applications such as tissue engineering and gene therapy is one of the major challenge approaches of regenerative medicine. In the field of adult stem cells, bone marrow stromal cells (BMSCs) are very promising candidates.
Esposito, Maria Teresa
core   +1 more source

The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

Frontiers in Immunology
BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM).
Lingling Yin, Lingling Yin, Lingling Yin, Bin Lv, Bin Lv, Jiao Ge, Yuekun Qi, Yuekun Qi, Yuekun Qi, Jieyun Xia, Jieyun Xia, Jieyun Xia, Sha Ma, Sha Ma, Sha Ma, Ying Wang, Ying Wang, Ying Wang, Yang Liu, Yang Liu, Yang Liu, Dian Zhou, Dian Zhou, Dian Zhou, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Kunming Qi, Kunming Qi, Kunming Qi, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Hai Cheng, Hai Cheng, Hai Cheng, Wei Chen, Wei Chen, Wei Chen, Kailin Xu, Kailin Xu, Kailin Xu, Weiying Gu, Zhenyu Li, Zhenyu Li, Zhenyu Li, Feng Zhu, Feng Zhu, Feng Zhu   +54 more
doaj   +1 more source

Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion

Haematologica, 2010
Background Lenalidomide improves erythropoiesis in patients with low/intermediate-1 risk myelodysplastic syndrome and interstitial deletion of the long arm of chromosome 5 [del(5q)].
Maria Ximeri, Athanasios Galanopoulos, Mirjam Klaus, Agapi Parcharidou, Krinio Giannikou, Maria Psyllaki, Argyrios Symeonidis, Vasiliki Pappa, Zafiris Kartasis, Dimitra Liapi, Eleftheria Hatzimichael, Styliani Kokoris, Penelope Korkolopoulou, Constantina Sambani, Charalampos Pontikoglou, Helen A. Papadaki   +15 more
doaj   +1 more source

Myelosuppressive conditioning using busulfan enables bone marrow cell accumulation in the spinal cord of a mouse model of amyotrophic lateral sclerosis. [PDF]

PLoS ONE, 2013
Myeloablative preconditioning using irradiation is the most commonly used technique to generate rodents having chimeric bone marrow, employed for the study of bone marrow-derived cell accumulation in the healthy and diseased central nervous system ...
Coral-Ann B Lewis, John Manning, Christine Barr, Kyle Peake, R Keith Humphries, Fabio Rossi, Charles Krieger   +6 more
doaj   +1 more source

A T Cell View of the Bone Marrow [PDF]

Frontiers in Immunology, 2016
The majority of T cells present in the bone marrow (BM) represent an activated/memory phenotype and most of these, if not all, are circulating T cells. Their lodging in the BM keeps them activated, turning the BM microenvironment into a "memory reservoir." This article will focus on how T cell activation in the BM results in both direct and indirect ...
Bonomo, Adriana, Monteiro, Ana Carolina, Gonçalves-Silva, Triciana, Cordeiro-Spinetti, Eric, Galvani, Rômulo Gonçalves, Balduino, Alex   +5 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Supersensitive PSA-Monitored neoadjuvant hormone treatment of clinically localized prostate cancer: Effects on positive margins, tumor detection and epithelial cells in bone marrow [PDF]

, 1998
Objective: The present study was done to investigate the effects of supersensitive PSA-controlled inductive treatment on positive margins, detection of tumor and epithelial cells in bone marrow of 101 patients with untreated and clinically localized ...
Köllermann, J., Kaulfuss, U., Spitz, J., Enzmann, Th., Köllermann M. W., Feek, U., Martell, W., Kossiwakis, M.   +7 more
core   +1 more source