Results 41 to 50 of about 632,495 (218)

Angiogenesis Induced by the Implantation of Self-Bone Marrow Cells: A New Material for Therapeutic Angiogenesis

Cell Transplantation, 2000
Bone marrow contains various primitive cells that are thought to secrete several angiogenic growth factors and may also differentiate into endothelial cells. The present study was conducted to investigate the possibility that bone marrow cells could be a
Kimikazu Hamano M.D., Tao-Sheng Li, Toshiro Kobayashi, Sei Kobayashi, Masunori Matsuzaki, Kensuke Esato   +5 more
doaj   +1 more source

A T Cell View of the Bone Marrow [PDF]

Frontiers in Immunology, 2016
The majority of T cells present in the bone marrow (BM) represent an activated/memory phenotype and most of these, if not all, are circulating T cells. Their lodging in the BM keeps them activated, turning the BM microenvironment into a "memory reservoir." This article will focus on how T cell activation in the BM results in both direct and indirect ...
Bonomo, Adriana, Monteiro, Ana Carolina, Gonçalves-Silva, Triciana, Cordeiro-Spinetti, Eric, Galvani, Rômulo Gonçalves, Balduino, Alex   +5 more
openaire   +2 more sources

Construction and validation of a nutritional status (CONUT)-based nomogram for predicting prolonged hematological toxicity in relapsed/refractory multiple myeloma after CAR-T cell therapy

Frontiers in Nutrition
Background aimChimeric antigen receptor (CAR)-T cell therapy is highly effective for relapsed/refractory multiple myeloma (R/R MM). Prolonged hematological toxicity (PHT) is a significant adverse event that adversely affects patient outcomes; however ...
Peng Xu, Peng Xu, Peng Xu, Xin-Ying Duan, Xin-Ying Duan, Xin-Ying Duan, Qi-Wen Feng, Qi-Wen Feng, Qi-Wen Feng, Ya-Wen Wang, Ya-Wen Wang, Ya-Wen Wang, Yang Liu, Yang Liu, Yang Liu, Huan-Xin Zhang, Huan-Xin Zhang, Huan-Xin Zhang, Kun-Ming Qi, Kun-Ming Qi, Kun-Ming Qi, Zhen-Yu Li, Zhen-Yu Li, Zhen-Yu Li, Qing-Yun Wu, Qing-Yun Wu, Qing-Yun Wu   +26 more
doaj   +1 more source

Effect of enkephalins on bone marrow cells

Biomedicine & Pharmacotherapy, 1992
Mouse bone marrow cells were incubated with methionine- or leucine-enkephalin (10(-15)-10(-6) M) before seeding into soft agar cultures. In marrow samples harvested at different times, enkephalins decreased GM colony count on average by 30-40%. In individual experiments, however, the same concentration of enkephalins caused even stimulation, or at ...
Križanac-Bengez, Ljiljana, Boranić, Milivoj, Testa, N.G., Marotti, Tatjana   +3 more
openaire   +3 more sources

Bone marrow derived cells as endothelial precursors and the role of multi-potent progenitor cells in repairing ischaemic tissues. [PDF]

, 2007
PhDIntroduction: Atherosclerosis and its complications are a major cause of death and disability and it remains a major challenge to develop new therapies for patients with irreversible end organ damage and ongoing ischaemia.
Wragg, Andrew
core  

Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]

, 2001
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin, Moosmann, Sabine, Wiest, Irmgard, Huss, Ralf, Meissner, Petra, Sagebiel, Sabine   +5 more
core   +1 more source

The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy

Frontiers in Immunology
BackgroundIn recent years, chimeric antigen receptor (CAR)-T cell therapy has achieved tremendous efficacy in relapsed/refractory multiple myeloma (R/R MM).
Lingling Yin, Lingling Yin, Lingling Yin, Bin Lv, Bin Lv, Jiao Ge, Yuekun Qi, Yuekun Qi, Yuekun Qi, Jieyun Xia, Jieyun Xia, Jieyun Xia, Sha Ma, Sha Ma, Sha Ma, Ying Wang, Ying Wang, Ying Wang, Yang Liu, Yang Liu, Yang Liu, Dian Zhou, Dian Zhou, Dian Zhou, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Kunming Qi, Kunming Qi, Kunming Qi, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Hai Cheng, Hai Cheng, Hai Cheng, Wei Chen, Wei Chen, Wei Chen, Kailin Xu, Kailin Xu, Kailin Xu, Weiying Gu, Zhenyu Li, Zhenyu Li, Zhenyu Li, Feng Zhu, Feng Zhu, Feng Zhu   +54 more
doaj   +1 more source

Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion

Haematologica, 2010
Background Lenalidomide improves erythropoiesis in patients with low/intermediate-1 risk myelodysplastic syndrome and interstitial deletion of the long arm of chromosome 5 [del(5q)].
Maria Ximeri, Athanasios Galanopoulos, Mirjam Klaus, Agapi Parcharidou, Krinio Giannikou, Maria Psyllaki, Argyrios Symeonidis, Vasiliki Pappa, Zafiris Kartasis, Dimitra Liapi, Eleftheria Hatzimichael, Styliani Kokoris, Penelope Korkolopoulou, Constantina Sambani, Charalampos Pontikoglou, Helen A. Papadaki   +15 more
doaj   +1 more source

Influence of Cytokines and Autologous Lymphokine-Activated Killer Cells on Leukemic Bone Marrow Cells and Colonies in AML [PDF]

, 2001
We have already shown that cytokine cocktails (IL-1 beta, IL-3, IL-6, SCF, GM-CSF) and/or lymphokine-activated killer (LAK) cells can reduce the amounts of clonal, CD34-positive mononuclear bone marrow cells (BM-MNC) in acute myeloid leukemia (AML).
Gerhartz, Helmut Heinrich, Schmetzer, Helga Maria, Braun, Susanne Walburg   +2 more
core   +1 more source

Bone marrow expands the repertoire of functional T cells targeting tumor-associated antigens in patients with resectable non-small-cell lung cancer

OncoImmunology, 2019
The efficacy of cancer immunotherapy may be improved by increasing the number of circulating tumor-reactive T cells. The bone marrow is a priming site and reservoir for such T cells.
Seyer Safi, Yoshikane Yamauchi, Slava Stamova, Anchana Rathinasamy, Jan op den Winkel, Simone Jünger, Mariana Bucur, Ludmilla Umansky, Arne Warth, Esther Herpel, Martin Eichhorn, Hauke Winter, Hans Hoffmann, Philipp Beckhove   +13 more
doaj   +1 more source