Results 21 to 30 of about 145,883 (307)

Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment

Breast Cancer Research, 2020
Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process.
Marie-Therese Haider, Hiroaki Saito, Jennifer Zarrer, Kevin Uzhunnumpuram, Sankari Nagarajan, Vijayalakshmi Kari, Michael Horn-Glander, Stefan Werner, Eric Hesse, Hanna Taipaleenmäki   +9 more
doaj   +1 more source

Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts

Frontiers in Bioengineering and Biotechnology, 2022
Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities.
Pan Liu, Pan Liu, Ji Tu, Wenzhao Wang, Zheng Li, Yao Li, Yao Li, Xiaoping Yu, Xiaoping Yu, Zhengdong Zhang, Zhengdong Zhang, Zhengdong Zhang   +11 more
doaj   +1 more source

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]

, 2009
We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I, Arnaud Scherberich, Montjovent, MO, Scherberich, A, Scherberich, Arnaud, Lee Ann Applegate, Montjovent, Marc-Olivier, Marc-Olivier Montjovent, Scaletta, Corinne, Dominique P. Pioletti, Bocelli-Tyndall, Chiara, Martin, Ivan, Applegate, LA, Laurent-Applegate, Lee, Bocelli-Tyndall, C., Pioletti, DP, Scherberich, A., Silke Mark, Montjovent, M.O., Scaletta, C, Pioletti, Dominique P., Mark, Silke, Mark, S., Bocelli-Tyndall, C, Applegate, Lee Ann, Mark, S, Pioletti, D.P., Corinne Scaletta, Scaletta, C., Ivan Martin, Martin, I., Applegate, L.A., Chiara Bocelli-Tyndall   +32 more
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Effect of diabetic osteoblasts on osteogenic differentiation of human umbilical cord mesenchymal stem cells

Biomedical Papers, 2015
Background: This study was aimed to investigate whether osteoblasts from diabetic patients have a promoting effect on osteogenesis of human umbilical cord mesenchymal stem cells (HUMSCs).
Ha Cheng-Zhi, Hai-Ying Chen, Juan Wang, Wei Liu, Ying-Xin Zhang, Li Pan, Wei-Hua Wang, Shuang-Feng Chen, Da-Wei Wang, Le-Xin Wang   +9 more
doaj   +1 more source

DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts

Cells, 2020
1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role ...
Sungsin Jo, Subin Yoon, So Young Lee, So Yeon Kim, Hyosun Park, Jinil Han, Sung Hoon Choi, Joong-Soo Han, Jae-Hyuk Yang, Tae-Hwan Kim   +9 more
doaj   +1 more source

Osteocytes but not osteoblasts directly build mineralized bone structures

, 2021
Bone-forming osteoblasts have been a cornerstone of bone biology for more than a century. Most research toward bone biology and bone diseases center on osteoblasts. Overlooked are the 90% of bone cells, called osteocytes.
Wang, Ke, Wang, Zheng, Chen, Lin, Yuan, X Baozhi, Xiao, Yin, Jing, Yan, Wang, Jun, Zheng, Minghao, Han, Xianglong, Zhao, Hu, Feng, Jian Q, Ren, Yinshi, Ma, Chi, Lin, Shuxian, Olsen, Bjorn Reino   +14 more
core   +1 more source

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
Mohammed Elsalanty, Jack C Yu, Cray, JJ, Elsalanty, M, Yu Jack C., James J Cray, Weinberg, SM, Khaksarfard Kameron, Cray, James J., Yu, JC, Khaksarfard, K, Yu, Jack C., Elsalanty, Mohammed, Kameron Khaksarfard, Weinberg Seth M., Weinberg, Seth M., Cray James J., Khaksarfard, Kameron, Seth M Weinberg, Elsalanty Mohammed   +19 more
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Comparison of the Anabolic Effects of Reported Osteogenic Compounds on Human Mesenchymal Progenitor-derived Osteoblasts

Bioengineering, 2020
There is variability in the reported effects of compounds on osteoblasts arising from differences in experimental design and choice of cell type/origin.
Robert Owen, Hossein Bahmaee, Frederik Claeyssens, Gwendolen C. Reilly   +3 more
doaj   +1 more source

Bone Cell Exosomes and Emerging Strategies in Bone Engineering

Biomedicines, 2022
Bone tissue remodeling is a highly regulated process balancing bone formation and resorption through complex cellular crosstalk between resident bone and microenvironment cells.
Sanjana Vig, Maria Helena Fernandes
doaj   +1 more source

Spreading area and shape regulate apoptosis and differentiation of osteoblasts [PDF]

, 2013
The in vivo observations have indicated that at the remodeling sites of bone, the spreading area or shape of preosteoblasts is confined by the mineralized matrix.
Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Inst Mech, Beijing 100190, Peoples R China., 刘琴丽, 龙勉, Guo XE, 霍波, Song GB, Baik A, 胡漫, 付瑞荣, 孙树津   +9 more
core   +1 more source