Results 21 to 30 of about 197,419 (304)

Serratiopeptidase reduces the invasion of osteoblasts by Staphylococcus aureus [PDF]

, 2017
Finding new strategies to counteract periprosthetic infection and implant failure is a main target in orthopedics. Staphylococcus aureus, the leading etiologic agent of orthopedic implant infections, is able to enter and kill osteoblasts, to stimulate ...
Arciola, Cr, Artini, M., Campoccia, D, Cellini, A, Ermocida, A, Ettorre, E, Montanaro, L, Papa, R, Selan, L, Vrenna, G   +9 more
core   +1 more source

Osteogenic effects of simvastatin-loaded mesoporous titania thin films [PDF]

, 2018
The use of statins in the field of bone regeneration is under current investigation due to the existing demand for non-toxic anabolic agents capable of enhancing bone formation in cases of substantial loss. Simvastatin, a coenzyme currently prescribed in
Angelome, Paula Cecilia, Gonzalez, Pio, Liz Marzan, Luis M, Lopez Alvarez, Miriam, López Puente, Vanesa, Pastoriza Santos, Isabel, Rodriguez Valencia, Cosme, Serra, Julia   +7 more
core   +1 more source

Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model. [PDF]

, 2014
The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic
Barrientos-Durán, Antonio, Carpenter, Ellen M, Malinin, Theodore I, Rodríguez-Manzaneque, Juan Carlos, Zanello, Laura P, Zur Nieden, Nicole I   +5 more
core   +2 more sources

Research Progress of Paradoxical Bone Formation in Osteoporosis [PDF]

Zhongguo quanke yixue
Osteoporosis is a common clinical bone disease caused by a variety of causes, it increases osteoclast production mainly by changing the inflammatory microenvironment of the body, the end result is increased bone resorption and decreased bone mass ...
YANG Yang, GAO Xi
doaj   +1 more source

Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]

, 2014
The basic mechanisms by which strontium ranelate acts on bone are still unclear. We show that an important action of strontium salts is to block calcification in cultures of osteoblasts, the bone-forming cells.
A Barbara, A Caudrillier, AF Donneau, AS Hurtel-Lemaire, C Roux, D. P. Wornham, E Bonnelye, E Canalis, F Yang, FE McCaslin, G Boivin, GJ Atkins, GM Blake, HB Pan, I Schrooten, I Schrooten, I Schrooten, I. R. Orriss, IR Orriss, IR Orriss, IR Orriss, J Christoffersen, JJ Patel, JY Reginster, JY Reginster, M Grynpas, M Yamaguchi, M. O. Hajjawi, MA Karsdal, MS Rybchyn, N Chattopadhyay, N Takahashi, O Bruyere, O Fromigue, P Ammann, P Zioupos, PC D’Haese, PJ Marie, PJ Marie, PJ Marie, PJ Marie, PJ Meunier, SC Verberckmoes, SC Verberckmoes, T. R. Arnett   +44 more
core   +3 more sources

Coumarin Ameliorates Impaired Bone Turnover by Inhibiting the Formation of Advanced Glycation End Products in Diabetic Osteoblasts and Osteoclasts

Biomolecules, 2020
Accumulating evidence demonstrates that the risk of osteoporotic fractures increases in patients with diabetes mellitus. Thus, diabetes-induced bone fragility has recently been recognized as a diabetic complication. As the fracture risk is independent of
Eun-Jung Lee, Min-Kyung Kang, Yun-Ho Kim, Dong Yeon Kim, Hyeongjoo Oh, Soo-Il Kim, Su Yeon Oh, Woojin Na, Young-Hee Kang   +8 more
doaj   +1 more source

MicroRNA-21: An Emerging Player in Bone Diseases

Frontiers in Pharmacology, 2021
MicroRNAs (MiRNAs) are small endogenous non-coding RNAs that bind to the 3′-untranslated region of target genes and promote their degradation or inhibit translation, thereby regulating gene expression. MiRNAs are ubiquitous in biology and are involved in
Chen Chen, Chen Chen, Ya-Mei Liu, Bin-Lan Fu, Liang-Liang Xu, Liang-Liang Xu, Bin Wang   +6 more
doaj   +1 more source

Osteoblast–osteoclast interactions [PDF]

Connective Tissue Research, 2017
Bone homeostasis depends on the resorption of bones by osteoclasts and formation of bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases such as osteoporosis. Thus, the mechanisms that regulate communication between osteoclasts and osteoblasts are critical to bone cell biology.
Xiao, Chen, Zhongqiu, Wang, Na, Duan, Guoying, Zhu, Edward M, Schwarz, Chao, Xie   +5 more
openaire   +2 more sources

Acid-Induced Inflammatory Cytokines in Osteoblasts: A Guided Path to Osteolysis in Bone Metastasis

Frontiers in Cell and Developmental Biology, 2021
Bone metastasis (BM) is a dismal complication of cancer that frequently occurs in patients with advanced carcinomas and that often manifests as an osteolytic lesion.
Gemma Di Pompo, Costantino Errani, Robert Gillies, Laura Mercatali, Toni Ibrahim, Jacopo Tamanti, Nicola Baldini, Nicola Baldini, Sofia Avnet, Sofia Avnet   +9 more
doaj   +1 more source

TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress [PDF]

, 2016
Background: Staphylococcus aureus is the principle causative pathogen of osteomyelitis and implant-associated bone infections. It is able to invade and to proliferate inside osteoblasts thus avoiding antibiotic therapy and the host immune system ...
Alt, Volker, Chakraborty, Trinad, Domann, Eugen, Heiss, Christian, Lips, Katrin S., Mannala, Gopala, Mohamed, Walid, Schnettler, Reinhard   +7 more
core   +2 more sources