Results 21 to 30 of about 136,319 (308)
Breast cancer bone metastases are attenuated in a Tgif1-deficient bone microenvironment
Breast Cancer Research, 2020 Background Osteoclast activation is a hallmark of breast cancer-induced bone disease while little is known about the role of osteoblasts in this process.
Marie-Therese Haider +9 more
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Effects of Mechanical Stress Stimulation on Function and Expression Mechanism of Osteoblasts
Frontiers in Bioengineering and Biotechnology, 2022 Osteoclasts and osteoblasts play a major role in bone tissue homeostasis. The homeostasis and integrity of bone tissue are maintained by ensuring a balance between osteoclastic and osteogenic activities.
Pan Liu +11 more
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Osteocytes but not osteoblasts directly build mineralized bone structures
, 2021 Bone-forming osteoblasts have been a cornerstone of bone biology for more than a century. Most research toward bone biology and bone diseases center on osteoblasts. Overlooked are the 90% of bone cells, called osteocytes.
Wang, Ke +14 more
core +1 more source
Biomedical Papers, 2015 Background: This study was aimed to investigate whether osteoblasts from diabetic patients have a promoting effect on osteogenesis of human umbilical cord mesenchymal stem cells (HUMSCs).
Ha Cheng-Zhi +9 more
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DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts
Cells, 2020 1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role ...
Sungsin Jo +9 more
doaj +1 more source
In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications [PDF]
, 2009 We describe herein some immunological properties of human fetal bone cells recently tested for bone tissue-engineering applications. Adult mesenchymal stem cells (MSCs) and osteoblasts were included in the study for comparison.
Martin, I +32 more
core +1 more source
Osteoblast biology: developmental origin and interactive nature of osteoblasts
, 2021 Bone formation occurs throughout life to support growth and bone remodeling in response to mechanical forces, metabolic needs, and tissue repair upon injury. The physiological requirement for continuous bone renewal to accommodate remodeling necessitates recruitment, proliferation, and differentiation of bone-forming osteoblasts to counteract the ...
van der Eerden, Bram C.J. +1 more
openaire +1 more source
Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]
, 2013 The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
Mohammed Elsalanty +19 more
core +1 more source
The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis
Brazilian Journal of Medical and Biological Research, 2005 Bone marrow stromal cells are critical regulators of hematopoiesis. Osteoblasts are part of the stromal cell support system in bone marrow and may be derived from a common precursor.
K. Neiva, Y.-X. Sun, R.S. Taichman
doaj +1 more source
Bioengineering, 2020 There is variability in the reported effects of compounds on osteoblasts arising from differences in experimental design and choice of cell type/origin.
Robert Owen +3 more
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