Results 11 to 20 of about 112,140 (265)
Inhibition of membrane RANKL production in osteoblasts mediates curcumin-inhibited osteoclastogenesis [PDF]
Brazilian Journal of Medical and Biological ResearchCurcumin inhibits osteoclastogenesis and mitigates osteoporosis. Our data demonstrated that curcumin decreases membrane-bound RANKL (mRANKL) levels on osteoblasts.
Tingwei Gao +3 more
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DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts
Cells, 2020 1α,25-dihydroxyvitamin D3 (1,25D3), the most popular drug for osteoporosis treatment, drives osteoblast differentiation and bone mineralization. Wnt/β-catenin signaling is involved in commitment and differentiation of osteoblasts, but the role ...
Sungsin Jo +9 more
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The role of osteoblasts in regulating hematopoietic stem cell activity and tumor metastasis
Brazilian Journal of Medical and Biological Research, 2005 Bone marrow stromal cells are critical regulators of hematopoiesis. Osteoblasts are part of the stromal cell support system in bone marrow and may be derived from a common precursor.
K. Neiva, Y.-X. Sun, R.S. Taichman
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Bioengineering, 2020 There is variability in the reported effects of compounds on osteoblasts arising from differences in experimental design and choice of cell type/origin.
Robert Owen +3 more
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Bone Cell Exosomes and Emerging Strategies in Bone Engineering
Biomedicines, 2022 Bone tissue remodeling is a highly regulated process balancing bone formation and resorption through complex cellular crosstalk between resident bone and microenvironment cells.
Sanjana Vig, Maria Helena Fernandes
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Metaplasia of Chondrocytes into Osteoblasts
Folia Biologica, 2006 Hypertrophic chondrocytes, commonly considered as terminal cells responsible for apoptotic elimination in endochondral osteogenesis, have the potential to switch their metabolic role and enter osteoblastic differentiation, based on histochemical, immunohistochemical, biochemical and cytological analysis.
Krzysztof H, Włodarski +2 more
openaire +2 more sources
Advanced Biomedical Research, 2012 Background: There are significant limitations in repair of irrecoverable bone defects. Stem-cell therapy is a promising approach for the construction of bone tissue.
Vahid Bahrambeigi +3 more
doaj +1 more source
Increased local bone turnover in patients with chronic periprosthetic joint infection
Bone & Joint Research, 2023 Aims: The management of periprosthetic joint infection (PJI) remains a major challenge in orthopaedic surgery. In this study, we aimed to characterize the local bone microstructure and metabolism in a clinical cohort of patients with chronic PJI ...
Nico Hinz +7 more
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Research Progress of Paradoxical Bone Formation in Osteoporosis [PDF]
Zhongguo quanke yixueOsteoporosis is a common clinical bone disease caused by a variety of causes, it increases osteoclast production mainly by changing the inflammatory microenvironment of the body, the end result is increased bone resorption and decreased bone mass ...
YANG Yang, GAO Xi
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Biomolecules, 2020 Accumulating evidence demonstrates that the risk of osteoporotic fractures increases in patients with diabetes mellitus. Thus, diabetes-induced bone fragility has recently been recognized as a diabetic complication. As the fracture risk is independent of
Eun-Jung Lee +8 more
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