Results 11 to 20 of about 4,254 (200)
Evaluation of <sup>161</sup>Tb-Labeled Diphosphonates as Potential Bone-Targeting Agents. [PDF]
Int J Mol SciTwo diphosphonates, etidronic acid (HEDP) and zoledronic acid (ZOL), were radiolabelled with 161Tb and evaluated as potential bone-targeting radiopharmaceuticals. Radiolabeling was performed at pH 7, achieving high radiolabeling yields (greater than 98%)
Sitarica P +9 more
europepmc +2 more sources
Renal secretion of diphosphonates in rats [PDF]
Kidney International, 1975 Diphosphonates, characterized by a P--C--P bond, are relatively new experimental drugs used for the treatment of myositis ossificans, dental calculus, nephrolithiasis and Paget's disease. These compounds are not metabolized and the fraction which is not taken up by the skeleton is excreted unchanged in the urine.
Troehler, Ulrich +2 more
openaire +3 more sources
Incidental finding of bone tracer accumulation in gastrointestinal stromal tumor: Two case reports [PDF]
Radiology Case ReportsBone scintigraphy with technetium-labelled diphosphonates is widely used for evaluating skeletal pathology. However, extra-osseous uptake may also be encountered and can indicate underlying neoplastic processes.
Gary Ka Wai Chan, MBChB +3 more
doaj +2 more sources
Effects of diphosphonates in disorders of bone turnover. [PDF]
, 1987 This thesis describes several interrelated studies concerning the effects of diphosphonates in the treatment of disorders of bone turnover. Diphosphonates have previously been shown to suppress bone turnover in Paget's disease when given orally for ...
Yates, Ashley John Paul
core +6 more sources
Clinical characteristics and prognosis of patients with chronic recurrent multifocal osteomyelitis based on cluster analysis: a 6-year cohort study [PDF]
Italian Journal of PediatricsBackground This multicenter study aimed to address the heterogeneity of chronic recurrent multifocal osteomyelitis (CRMO) by identifying clinical subtypes through cluster analysis, exploring clinical features, treatment approaches, and short-term ...
Tong Yue +15 more
doaj +2 more sources
Review and Update of the Risk Factors and Prevention of Antiresorptive-Related Osteonecrosis of the Jaw [PDF]
Endocrinology and Metabolism, 2021 Antiresorptive-related osteonecrosis of the jaw (ARONJ) is a rare but serious adverse event of bisphosphonate or denosumab administration; it is associated with severe pain and a deteriorated quality of life.
Ha Young Kim
doaj +1 more source
Molecules, 2022 All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained.
Liwia Lebelt +2 more
doaj +1 more source
Long-Term Treatment of Postmenopausal Osteoporosis [PDF]
Endocrinology and Metabolism, 2021 Osteoporosis is an incurable chronic condition, like heart disease, diabetes, or hypertension. A large gap currently exists in the primary prevention of fractures, and studies show that an estimated 80% to 90% of adults do not receive appropriate ...
Jacques P. Brown
doaj +1 more source
, 1996 Molecular modeling techniques are used to investigate the interaction of alkyldiphosphonate molecular anions with the surfaces of barium sulfate. We show that the most stable sites are on the (100) and (011) surfaces with the [PO3]2- groups of the ...
Gay, D. H. +3 more
core +10 more sources
Effects of red and infrared laser on post extraction socket repair in rats subjected to alendronate therapy [PDF]
Brazilian Oral Research, 2023 This study evaluated the effect of photobiomodulation therapy (PBMT) with a red or infrared laser on the repair of post extraction sockets in rats administered alendronate (ALN).
Fernanda Castanheira GONÇALVES +4 more
doaj +1 more source