Results 21 to 30 of about 3,779 (178)

Microscopic Evaluation of the Effect of Oral Microbiota on the Development of Bisphosphonate-Related Osteonecrosis of the Jaws in Rats

open access: yeseJournal of Oral Maxillofacial Research, 2017
Objectives: Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats ...
Felipe M. Silveira   +3 more
doaj   +1 more source

DIPHOSPHONATES IN PAGET'S DISEASE

open access: yesThe Lancet, 1974
Abstract The diphosphonate, sodium etidronate (disodium ethane-1-hydroxy-1,1-diphosphonate) (E.H.D.P.), which inhibits the growth and dissolution of calcium phosphate crystals in vitro, was given at doses of 0, 1, 5, 10, or 20 mg. per kg. per day for up to 6 months to forty-seven patients with Paget's disease of bone.
Russell, R   +4 more
openaire   +2 more sources

Severe congestive heart failure in elderly patient with Paget’s disease

open access: yesGeriatric Care, 2017
Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj   +1 more source

Efficacy of combination therapy of vitamin D and bisphosphonates in the treatment of postmenopausal osteoporosis: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology
ObjectiveThere is currently no consensus on whether the combination therapy of Vitamin D (VitD) and bisphosphonates offers superior efficacy compared to monotherapy in the treatment of postmenopausal osteoporosis.
Yuangui Yang   +3 more
doaj   +1 more source

Liver metastasis of lung cancer detected with similar uptake pattern on bone scintigraphy and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography: What's the pathophysiologic mechanism?

open access: yesWorld Journal of Nuclear Medicine, 2017
Bone scintigraphy with 99mTc diphosphonates may exhibit extraosseous lesions in addition to metastatic lesions. Multiple factors can affect extraosseous 99mTc methylene diphosphonate (MDP) uptake.
Funda Üstün   +3 more
doaj   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 11, November 2026.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen   +8 more
wiley   +1 more source

PROFILAKTIKA NARUPENI OBMENA KAL'TsIYa I SISTEM EGO REGULYaTsII PRI DLITEL'NOY GIPOKINEZII S UChASTIEM ChELOVEKA

open access: yesОстеопороз и остеопатии, 2007
In conditions of 120-daily bedrest changes of a metabolism of the calcium, the functions of a bone directed on preservation at a necessary level of a bone material at the maximal economy level in these conditions were studied.
O I ORLOV
doaj   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 11, November 2026.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang   +11 more
wiley   +1 more source

Pamidronato dissódico (APD) no tratamento das metástases ósseas.

open access: yesActa Médica Portuguesa, 1993
Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution ...
L Costa, C Moreira, E B da Costa
doaj   +1 more source

Aneurysmal Bone Cyst of the Radial Diaphysis Managed by En Bloc Resection and Fibular Strut Autograft Reconstruction in a Young Adult Female: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Aneurysmal bone cyst (ABC) of the radial diaphysis is rare and may mimic telangiectatic osteosarcoma on imaging. We report a young woman with progressively enlarging, painful forearm swelling due to ABC, treated by en bloc resection and fibular strut autograft reconstruction, achieving pain‐free union, good function and no recurrence at short ...
Abdul Hadi Khan   +6 more
wiley   +1 more source

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