Results 21 to 30 of about 3,779 (178)
Objectives: Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats ...
Felipe M. Silveira +3 more
doaj +1 more source
DIPHOSPHONATES IN PAGET'S DISEASE
Abstract The diphosphonate, sodium etidronate (disodium ethane-1-hydroxy-1,1-diphosphonate) (E.H.D.P.), which inhibits the growth and dissolution of calcium phosphate crystals in vitro, was given at doses of 0, 1, 5, 10, or 20 mg. per kg. per day for up to 6 months to forty-seven patients with Paget's disease of bone.
Russell, R +4 more
openaire +2 more sources
Severe congestive heart failure in elderly patient with Paget’s disease
Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj +1 more source
ObjectiveThere is currently no consensus on whether the combination therapy of Vitamin D (VitD) and bisphosphonates offers superior efficacy compared to monotherapy in the treatment of postmenopausal osteoporosis.
Yuangui Yang +3 more
doaj +1 more source
Bone scintigraphy with 99mTc diphosphonates may exhibit extraosseous lesions in addition to metastatic lesions. Multiple factors can affect extraosseous 99mTc methylene diphosphonate (MDP) uptake.
Funda Üstün +3 more
doaj +1 more source
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen +8 more
wiley +1 more source
In conditions of 120-daily bedrest changes of a metabolism of the calcium, the functions of a bone directed on preservation at a necessary level of a bone material at the maximal economy level in these conditions were studied.
O I ORLOV
doaj +1 more source
pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang +11 more
wiley +1 more source
Pamidronato dissódico (APD) no tratamento das metástases ósseas.
Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution ...
L Costa, C Moreira, E B da Costa
doaj +1 more source
ABSTRACT Aneurysmal bone cyst (ABC) of the radial diaphysis is rare and may mimic telangiectatic osteosarcoma on imaging. We report a young woman with progressively enlarging, painful forearm swelling due to ABC, treated by en bloc resection and fibular strut autograft reconstruction, achieving pain‐free union, good function and no recurrence at short ...
Abdul Hadi Khan +6 more
wiley +1 more source

