Results 71 to 80 of about 563,982 (335)

When the optimal is not the best: parameter estimation in complex biological models [PDF]

, 2010
Background: The vast computational resources that became available during the past decade enabled the development and simulation of increasingly complex mathematical models of cancer growth.
A Björck, A Gara, B Gompertz, BC Daniels, C Kreutz, C Moles, Cecilia Suárez, D Fernández Slezak, D Marquardt, Darren R. Flower, Diego Fernández Slezak, E Marinari, F James, G Cedersund, G Fracasso, Guillermo A. Cecchi, Guillermo Marshall, Gustavo Stolovitzky, H Kitano, IT Jolliffe, J Freyer, J Freyer, J Freyer, J Freyer, J Nelder, J Ward, JW Zwolak, JW Zwolak, K Levenberg, L Kunz-Schughart, L Preziosi, M Ashyraliyev, M Marusic, M Marusic, M Rodriguez-Fernandez, N Adiga, P Pacheco, R Araujo, R Fletcher, R Gutenkunst, R Sutherland, S Wise, Y Jiang   +42 more
core   +6 more sources

Avascular Necrosis of Femoral Head: A Metabolomic, Biophysical, Biochemical, Electron Microscopic and Histopathological Characterization

Scientific Reports, 2017
Avascular necrosis of the femur head (AVNFH) is a debilitating disease caused due to the use of alcohol, steroids, following trauma or unclear (idiopathic) etiology, affecting mostly the middle aged population.
Aswath Narayanan, P. Khanchandani, Roshan M. Borkar, Chandrashekar Reddy Ambati, A. Roy, Xu Han, Ritesh N Bhoskar, Srinivas Ragampeta, F. Gannon, V. Mysorekar, Balasubramanyam Karanam, S. V, Venketesh Sivaramakrishnan   +12 more
semanticscholar   +1 more source

Osteonecrosis in genetic disorders [PDF]

, 2007
The avascular necrosis of bone is characterized by an abnormality of tissue that can occur whenever a disease process causes major cell stress. Some evidence supports a role for genetic factors in some avascular necrosis suggesting that gene mutations ...
Brandi, Maria Luisa, Falchetti, Alberto, Masi, Laura   +2 more
core  

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado, Erika N. Scott, Shahrad R. Rassekh, Catrina M. Loucks, Wan‐Chun Chang, Edward J. Raack, Jessica N. Trueman, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety Consortium   +9 more
wiley   +1 more source

MR imaging of avascular scaphoid nonunion before and after vascularized bone grafting [PDF]

, 2018
Objective: To investigate the magnetic resonance (MR) imaging appearances of chronic nonunion of the scaphoid with proximal pole avascular necrosis before and after insertion of a vascularized bone graft, using computed tomography (CT) as the imaging ...
Anderson, Suzanne, Martin, Matthias, Nagy, Ladislav, Steinbach, Lynne, Tschering-Vogel, Dechen   +4 more
core  

First report of multi-drug resistant tuberculosis in a systemic lupus erythematosus patient. [PDF]

, 2015
BackgroundTreatment of a multi-drug resistant tuberculosis (MDR-TB) patient is clinically challenging, requiring a minimum of 18 months of therapy. Its occurrence in a systemic lupus erythromatosus (SLE) patient may complicate management of both MDR-TB ...
Dierberg, Kerry L, Dorjee, Kunchok, Reingold, Arthur L, Sadutshang, Tsetan D   +3 more
core   +1 more source

Core decompression and biotechnologies in the treatment of avascular necrosis of the femoral head

EFORT Open Reviews, 2017
Avascular necrosis (AVN) of the femoral head (FH) causes 5% to 12% of total hip arthroplasties (THA). It especially affects active male adults between the third and fifth decades of life. The exact worldwide incidence is unknown.
G. Calori, E. Mazza, A. Colombo, S. Mazzola, M. Colombo   +4 more
semanticscholar   +1 more source

Evaluation of the Baseplate Position and Screws in Reverse Total Shoulder Arthroplasty Using 3D Printed Patient‐Specific Instrumentation

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Patient‐specific instrumentation (PSI) in shoulder arthroplasty has been used to translate preoperative surgical planning into precise implant positioning. However, screws for baseplate fixation using PSI have not been preoperatively planned or verified for proper location and length.
Wonhee Lee, Woojin Yu, HwaYong Lee, Guk Bae Kim, In‐Ho Jeon, Kyoung Hwan Koh   +5 more
wiley   +1 more source

In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino, Francesca De Vecchi, Takayuki Koya, Landon M. Begin, Douglas C. Moore, Joseph J. Crisco, Markus A. Wimmer   +6 more
wiley   +1 more source

Mathematical models of avascular cancer [PDF]

, 2005
This review will outline a number of illustrative mathematical models describing the growth of avascular tumours. The aim of the review is to provide a relatively comprehensive list of existing models in this area and discuss several representative ...
Chapman, S. J., Maini, P. K., Roose, T.
core