Results 41 to 50 of about 652,829 (286)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Quality Improvement on RoF 5G Fronthaul System Design at Millimeter-wave with EDFA and FBG Techniques

Jurnal Elkomika, 2023
ABSTRAK Jaringan seluler terkini membutuhkan kapasitas tinggi dan latensi rendah di fronthaul yang dapat didukung oleh radio over fiber (RoF) dengan gelombang milimeter.
CATUR APRIONO, SALSABILA SHITA PUTRI NUGROHO, YUS NATALI   +2 more
doaj   +1 more source

Sum-rate maximisation comparison using incremental approaches with different constraints [PDF]

, 2009
In this work, the problem of rate maximisation of multichannel systems is considered. Two greedy allocation approaches using power (GPA) and bit (GBA) loading schemes with a slight difference in design constraints that aiming to maximise the overall ...
Al-Hanafy, Waleed, Weiss, S.
core  

Adaptive Subcarrier PSK Intensity Modulation in Free Space Optical Systems [PDF]

, 2010
We propose an adaptive transmission technique for free space optical (FSO) systems, operating in atmospheric turbulence and employing subcarrier phase shift keying (S-PSK) intensity modulation.
Athanasios S. Lioumpas, George K. Karagiannidis, Nestor D. Chatzidiamantis, Senior Member, Senior Member, Shlomi Arnon, Student Member   +6 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Blind Detection for Serial Relays in Free Space Optical Communication Systems

Applied Sciences, 2018
Free-space optical (FSO) communication systems have attracted considerable research interest owing to its high transmission rates and its efficient solution for the last mile problem. Atmospheric turbulence degrades the performance of FSO systems.
Mohamed Elbawab, Mohamed Abaza, Moustafa H. Aly   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

On the Complexity of Exact Maximum-Likelihood Decoding for Asymptotically Good Low Density Parity Check Codes: A New Perspective [PDF]

, 2007
The problem of exact maximum-likelihood (ML) decoding of general linear codes is well-known to be NP-hard. In this paper, we show that exact ML decoding of a class of asymptotically good low density parity check codes — expander codes — over binary ...
Hassibi, Babak, Xu, Weiyu
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source