Results 71 to 80 of about 6,160,028 (209)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dynamics of Eucalyptus Diameter Distribution in the State of Minas Gerais
The aim of this study was to evaluate the effects of age, site, and density factors on the dynamics of eucalyptus diameter distribution. Data were obtained from a continuous forest inventory measured at different occasions, stratified according to the ...
Luciane Naimeke Schmidt +3 more
doaj +1 more source
Density of clinical trial sites (per million people) by country, ranked by average annual trial density 2006–2012.
Paul K. Drain (286784) +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Many humans live in large, complex political centers, composed of multi-scalar communities including neighborhoods and districts. Both today and in the past, neighborhoods form a fundamental part of cities and are defined by their spatial, architectural,
Amy E. Thompson +31 more
doaj
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Average power spectrum density of subjects at different stimulation frequencies.
(a) Average power spectrum density of subjects at 11 Hz. Equal-luminance red-green checkerboard induced higher EEG SNR. (b) Average power spectrum density of subjects at 16 Hz. The differences of the two paradigms are not significant.
Ailing Luo (3623249) +7 more
core +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Network Properties: number of nodes, number of edges, average (out) degree, degree assortativity, network density, average clustering coefficient.
Jose Anson (2818627) +4 more
core +1 more source

