Results 101 to 110 of about 2,196,882 (335)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A Dynamic Analysis of Moving Average Rules [PDF]

open access: yes
The use of various moving average rules remains popular with financial market practitioners. These rules have recently become the focus of empirical studies.
Carl Chiarella   +2 more
core   +3 more sources

Empirical Bayes Prediction for an Attribute Control Chart in Quality Monitoring

open access: yesIEEE Access
A control chart is a valuable statistical tool used in production process control to ensure that products meet quality standards. The c-chart, a specific type of control chart, monitors the number of nonconformities or defects in a production process ...
Yadpirun Supharakonsakun
doaj   +1 more source

Mixed Control Charts Using EWMA Statistics

open access: yesIEEE Access, 2016
In this paper, two mixed control charts are designed for process monitoring when the quality characteristic of interest follows a normal distribution.
Muhammad Aslam   +3 more
doaj   +1 more source

An Expected Average Run Length (EARL) Performance Comparison of the SSGR and EWMA Control Charts

open access: diamond, 2023
Huay Woon You   +9 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

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