Results 141 to 150 of about 26,494,628 (344)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Spectrum sensing algorithm based on average value of middle part of power spectral density
The difference between maximum and minimum value of the received signal power spectrum is distinct when the primary user signal is present or absent.Using this characteristic,the spectrum sensing algorithm based on the average of the middle part of power
Zhijin ZHAO, Xi LV, Shilian ZHENG
doaj +2 more sources
Scientific Opinion on Dietary Reference Values for calcium
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies derived Dietary Reference Values for calcium.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj +1 more source
ANALISA KEANDALAN SISTEM DISTRIBUSI 20 kV PADA PENYULANG PT. PLN (PERSERO) ULP TANJUNG MENGGUNAKAN METODE SECTION TECHNIQUE-RIA [PDF]
Resilience and reliability in distributing electricity is crucial and needs to always be maintained in order to meet consumer needs. Several aspects that indicate the reliability of an electricity distribution system include the continuity of the ...
Charismanda, M. Andre
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Analysis of converter-permanent magnet synchronous machine set by improved average-value modeling
Dc excitation of the field winding in a synchronous machine can be provided by permanent magnets. Permanent magnet synchronous machine (PMSM) can offer simpler construction, lower weight and size for the same performance, with reduced losses and higher ...
A.Vahedi, M.Ramezani
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Leximals, the Lexicore and the Average Lexicographic Value [PDF]
The lexicographic vectors of a balanced game, called here leximals, are used to define a new solution concept, the lexicore, on the cone of balanced games. Properties of the lexicore and its relation with the core on some classes of games are studied. It
Brânzei, R., Funaki, Y., Tijs, S.H.
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

