Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Research on a Miniaturized Digital Servo System for Passive Hydrogen Masers. [PDF]
Guo S +5 more
europepmc +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Optimization of Diffusion MRI With Consideration of the Signal Decay in Biological Tissues. [PDF]
Kuczera S, Maier SE.
europepmc +1 more source
Swedish Method and Volume Averaging Technique in Deep Mixing analysis
Ground improvement methods are commonly used to improve the stiffness and the settlement of soft soils. Deep mixing method using grouting additives is one of these ground improvement methods.
Sheikho, Sameer
core
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
HDFusion: Hierarchical Data Fusion for Robust Fetal Heart Rate Estimation using Transabdominal PPG Signals. [PDF]
Lihe T, Kasap B, Vali K, Ghiasi S.
europepmc +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Validation of absolute dose calculation of a single 125I-seed for ophthalmic brachytherapy within distance range 1-15 mm using a diode detector. [PDF]
Rintala A +3 more
europepmc +1 more source

