Results 61 to 70 of about 158,159 (215)

A Case of Sepsis Caused by ST80 Multidrug‐Resistant Enterococcus faecium With Concurrent Klebsiella pneumoniae Infection in a Dog

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
An 8‐year‐old dog developed acute respiratory distress that progressed to sepsis and death. Multidrug‐resistant Enterococcus faecium ST80 was isolated from the liver and kidney, while Klebsiella pneumoniae was detected in the lung by PCR. Whole‐genome sequencing showed that the ST80 isolates were genetically identical, suggesting hematogenous spread ...
Hyung‐min Seo, Tae‐Min La, Ye‐ram Seo, Dong‐Yeop Lee, Hyun‐Jung Han, Ji‐Yeon Hyeon   +5 more
wiley   +1 more source

Isolation, identification and molecular characterization of Inclusion body hepatitis virus [PDF]

Veterinary World, 2010
Inclusion body hepatitis caused by avian adenovirus with highly pathogenic strain lead to heavy mortality and unusual lesion like hydropericardium in commercial broilers.
Amit Gaba, Hitesh Parmar, J.K.Pal and K.S.Prajapati1   +2 more
doaj  

Bovine Adenovirus Vectored Vaccine for Avian Influenza

Molecular Therapy, 2008
Reports of avian influenza in humans over the past several years have raised concerns about a potential H5N1 influenza pandemic. The development of a vaccine against H5N1 influenza is therefore an important research priority. In this issue of Molecular Therapy, Singh and colleagues1 report the construction of a bovine adenovirus serotype 3 (BAd3)–based
openaire   +2 more sources

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, Volume 13, Issue 21, 13 April 2026.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, Volume 36, Issue 26, 30 March 2026.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Altering the Ad5 packaging domain affects the maturation of the Ad particles [PDF]

, 2011
We have previously described a new family of mutant adenoviruses carrying different combinations of attB/attP sequences from bacteriophage PhiC31 flanking the Ad5 packaging domain.
Alba Fernández, Raúl, Raul Alba, Assumpcio Bosch, Chillon Miguel, Philomena Ostapchuk, Cots Dan, Hearing Patrick, Hearing, P., Alba, R., Ostapchuk Philomena, Bosch i Merino, Assumpció, Ostapchuk, Philomena, Alba Raul, Bosch Assumpcio, Miguel Chillon, Ostapchuk, P., Cots i Rabella, Dan, Cots, D., Chillón Rodríguez, Miguel, Chillon, M., Patrick Hearing, Hearing, Patrick, Bosch, A., Dan Cots   +23 more
core   +2 more sources

Drivers of Viral Diversity and Sharing in Marine Mammals

Molecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Knowledge of viral infection in marine mammals, a group severely threatened by human activity, is largely limited to the pathology and epidemiology of few endemic viruses. The recent emergence in marine mammals of high‐consequence viruses, such as H5N1 avian influenza and rabies, underscores the importance of understanding the ecology of viral
Matthew J. Arnold, Laura M. Bergner, Haris Malik, Mariel ten Doeschate, Nicholas J. Davison, Andrew Brownlow, Nardus Mollentze, Simon A. Babayan, Daniel G. Streicker   +8 more
wiley   +1 more source

A porcine adenovirus with low human seroprevalence is a promising alternative vaccine vector to human adenovirus 5 in an H5N1 virus disease model. [PDF]

PLoS ONE, 2010
Human adenovirus 5 (AdHu5) vectors are robust vaccine platforms however the presence of naturally-acquired neutralizing antibodies may reduce vector efficacy and potential for re-administration.
Ami Patel, Suresh Tikoo, Gary Kobinger
doaj   +1 more source

Characterising the Transcriptomic Response to Interferon and Infection in European Domestic Ferret Respiratory Tissues Using Long‐Read RNA Sequencing

Immunology, Volume 177, Issue 2, Page 299-316, February 2026.
We utilised long‐read Nanopore sequencing to characterise the transcriptome of ferret cell lines stimulated with IFN‐α as well as nasal turbinates from ferrets infected with influenza A virus. We identified novel genes and isoforms and observed elongation of poly(A) tails in the ribosome and Coronavirus Disease‐19 pathways in response to IFN‐α ...
Rubaiyea Farrukee, Jessie J.‐Y. Chang, Jianshu Zhang, James B. Barnes, Shu Xin Zhang, Sher Maine Tan, Patrick C. Reading, Lachlan J. M. Coin   +7 more
wiley   +1 more source