Results 1 to 10 of about 768,440 (168)

Characterization of the hepatitis B virus DNA detected in urine of chronic hepatitis B patients

BMC Gastroenterology, 2018
Background Detection of human hepatitis B virus (HBV) DNA in the urine of patients with chronic hepatitis B infection (CHB) has been reported previously, suggesting urine could provide a potential route of horizontal HBV transmission.
Surbhi Jain, Ying-Hsiu Su, Yih-Ping Su, Sierra McCloud, Ruixia Xue, Tai-Jung Lee, Shu-Chuan Lin, Selena Y. Lin, Wei Song, Jamin D. Steffen, Chi-Tan Hu   +10 more
doaj   +1 more source

Measuring turnover of SIV DNA in resting CD4+ T cells using pyrosequencing: implications for the timing of HIV eradication therapies.

PLoS ONE, 2014
Resting CD4+ T cells are a reservoir of latent HIV-1. Understanding the turnover of HIV DNA in these cells has implications for the development of eradication strategies.
Jeanette C Reece, Alexey Martyushev, Janka Petravic, Andrew Grimm, Shayarana Gooneratne, Thakshila Amaresena, Robert De Rose, Liyen Loh, Miles P Davenport, Stephen J Kent   +9 more
doaj   +1 more source

Viral Genomic DNA Packaging Machinery

Tailed double-stranded DNA bacteriophage employs a protein terminase motor to package their genome into a preformed protein shell-a system shared with eukaryotic dsDNA viruses such as herpesviruses. DNA packaging motor proteins represent excellent targets for antiviral therapy, with Letermovir, which binds Cytomegalovirus terminase, already licensed as
Hawkins, Dorothy E D P, Godwin, Owen C, Antson, Alfred A   +2 more
openaire   +3 more sources

Evidence for a newly discovered triallelic pattern in the human STR D1S1656 locus

Biotechnology & Biotechnological Equipment
In this study, we report a case of a previously undetected triallelic pattern in the arrangement of structures at the D1S1656 locus in the Bulgarian population.
Vera Djeliova, Tsanko Markov, Stanislava Dimitrova-Nikolova, Dimo Krastev, Milka Mileva, Aleksandar Apostolov   +5 more
doaj   +1 more source

The C4 protein encoded by tomato leaf curl Yunnan virus reverses transcriptional gene silencing by interacting with NbDRM2 and impairing its DNA-binding ability

PLoS Pathogens, 2020
In plants, cytosine DNA methylation is an efficient defense mechanism against geminiviruses, since methylation of the viral genome results in transcriptional gene silencing (TGS).
Yuzhen Mei, Yaqin Wang, Fangfang Li, Xueping Zhou, Savithramma P. Dinesh-Kumar   +4 more
doaj  

Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

mBio, 2018
High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated-dependent DNA-related (ATR) pathway in the absence of external DNA damaging agents for ...
Kavi Mehta, Laimonis Laimins
doaj   +1 more source

Multiplex gene editing suppresses random integration of hepatitis B virus DNA in chronically infected liver

Molecular Therapy: Nucleic Acids
Gene editing technologies have opened the possibility of directly targeting viral DNA for therapeutic applications. In chronically infected hepatocytes with hepatitis B virus (HBV), covalently closed circular DNA (cccDNA) serves as the master template ...
Samuel Slattery, Wenwen Huo, Amena Arif, Jennifer Gordon, Ryo Takeuchi   +4 more
doaj   +1 more source

Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex.

PLoS Pathogens, 2017
Productive infection of human parvovirus B19 (B19V) exhibits high tropism for burst forming unit erythroid (BFU-E) and colony forming unit erythroid (CFU-E) progenitor cells in human bone marrow and fetal liver.
Safder S Ganaie, Wei Zou, Peng Xu, Xuefeng Deng, Steve Kleiboeker, Jianming Qiu   +5 more
doaj   +1 more source

Global diversity and biogeography of DNA viral communities in activated sludge systems. [PDF]

Microbiome, 2023
Fan X, Ji M, Mu D, Zeng X, Tian Z, Sun K, Gao R, Liu Y, He X, Wu L, Li Q.   +10 more
europepmc   +1 more source

CXCL10 Chemokine: A Critical Player in RNA and DNA Viral Infections. [PDF]

Viruses, 2022
Elemam NM, Talaat IM, Maghazachi AA.
europepmc   +1 more source