Immunoinformatics, molecular docking and dynamics simulation approaches unveil a multi epitope-based potent peptide vaccine candidate against avian leukosis virus. [PDF]
Lymphoid leukosis is a poultry neoplastic disease caused by avian leukosis virus (ALV) and is characterized by high morbidity and variable mortality rates in chicks. Currently, no effective treatment and vaccination is the only means to control it.
Elshafei SO, Mahmoud NA, Almofti YA.
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Simultaneous Detection of Three Subgroups of Avian Leukosis Virus Using the Nanoparticle-Assisted PCR Assay [PDF]
Nanoparticle-assisted polymerase chain reaction (nanoPCR) is a novel method for the rapid detection of pathogens. A sensitive and specific multiple nanoPCR assay was developed for simultaneous detection of avian leucosis virus (ALV) subgroups A, B and J.
Miaoli Wu +4 more
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Subgroup J avian leukosis virus (ALV-J), an oncogenic retrovirus, causes hemangiomas and myeloid tumors in chickens. We previously showed that miR-125b is down-regulated in ALV-J-induced tumors.
Chaoqi Ren +20 more
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Effect of Diet on Avian Leukosis
Abstract Boyd and Edwards (1966) showed that chickens fed diets deficient in essential fatty acids (EFA) or containing primarily saturated fat had high mortality when inoculated with Escherichia coli. In order to determine if other disease agents may cause the same effect, the diets described in the previous study were utilized and one-day-old chicks
F M, Boyd, H M, Edwards
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Multi-clade co-evolution and differential replication efficiencies of subgroup A avian leukosis virus in Chinese guinea fowl. [PDF]
Chen J +8 more
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Detection and genetic diversity of subgroup K avian leukosis virus in local chicken breeds in Jiangxi from 2021 to 2023 [PDF]
Avian leukosis virus subgroup K (ALV-K) is a new subgroup of avian leukosis virus (ALV) that was first identified in Chinese native chickens in recent years. To further understand the molecular epidemiology and evolutionary diversity of ALV-K, this study
Fanfan Zhang +6 more
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Specificity of avian leukosis virus-induced hyperlipidemia [PDF]
Rous-associated virus 7 (RAV-7) is a subgroup C avian leukosis virus which does not transform cells in vitro or carry an oncogene. When injected into 1-day-old hatched chicks, RAV-7 causes a low incidence of lymphoid leukosis after a latent period of several months.
J K, Carter, R E, Smith
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Specific and Sensitive Visual Proviral DNA Detection of Major Pathogenic Avian Leukosis Virus Subgroups Using CRISPR-Associated Nuclease Cas13a [PDF]
Avian leukosis viruses (ALVs) include a group of avian retroviruses primarily associated with neoplastic diseases in poultry, commonly referred to as avian leukosis. Belonging to different subgroups based on their envelope properties, ALV subgroups A, B,
Qingqing Xu +10 more
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Avian leukosis virusāreceptor interactions [PDF]
Cellular receptors for subgroups A, B, D and E avian leukosis virus (ALV) have been identified and characterized. The Tva receptor for subgroup A ALV is a member of the low density lipoprotein receptor family of proteins. There is an accumulating body of evidence to suggest that this receptor binds specifically to subgroup A viral envelope (Env ...
John A. T. Young
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Avian leukosis virus usurps the cellular SERBP1 protein to enhance its transcription and promote productive infections in avian cells [PDF]
: Avian leukosis virus subgroup K (ALV-K) is composed of newly emerging isolates, which cluster separately from the well-characterized subgroups A, B, C, D, E, and J in sequence analysis, and exhibits a specific host range and a unique pattern of ...
Ning Cui +6 more
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