Intravital Imaging of Immune Responses in the Cancer Microenvironment
ABSTRACT Background To date, many types of immune cells have been identified, but their precise role in cancer immunity remains unclear. Understanding the immune responses involved in cancer and the cancer microenvironment is becoming increasingly important for elucidating disease mechanisms.
Hiroki Hirao +6 more
wiley +1 more source
PCR Based Evidence of Reticuloendotheliosis Virus Infection in Chickens from Turkey [PDF]
In this study, presence of avian leukosis virus (ALV) and reticuloendotheliosis virus (REV) was investigated in neoplastic cases observed in breeder hens older than 20 weeks in commercial broiler breeders. Tumor samples were examined by PCR combined with
Hasan Ongor and Hakan Bulut1*
doaj
A possible mechanism of RNA replication in Rous sarcoma virus [PDF]
Partially separated double-stranded RNA from purified Rous sarcoma virus, Schmidt.Ruppin strain, was observed by electron microscopy utilizing 8.M urea and protein monolayer technique.
Oda, Takuzo, Ogura, Hajime
core +1 more source
The ageing virus hypothesis: Epigenetic ageing beyond the Tree of Life
Viruses would age when the epigenetic signals they need to carry out their life cycle are degraded. Given the abundance and age of viruses, epigenetic aging of viruses would extend theories on the evolution of aging beyond cellular organisms, and encourage new models of viral dynamics and new anti‐viral therapies.
Éric Bapteste
wiley +1 more source
Prolactin: A Key Immunoregulator in Viral Infections and Autoimmune Diseases
Prolactin (PRL) is secreted by various cells in the anterior pituitary gland, mammary glands, placenta, uterus, ovaries, testes, skin, adipose tissue, endothelial cells, immune system, and central nervous system. The expression and secretion of PRL are influenced by several factors such as suckling, thyrotropin‐releasing hormone (TRH), cytokines ...
Mina Asadikaram +6 more
wiley +1 more source
Avian Adenoviruses Infections with Special Attention to Inclusion Body Hepatitis/ Hydropericardium Syndrome and Egg Drop Syndrome [PDF]
The first avian adenovirus (AAV) associated with clinical disease was isolated from an outbreak of respiratory disease in quail in 1950 (Olson, 1950). Since that time, AAVs have been found in all types and breeds of chickens and from a variety of other ...
Hafez, Hafez Mohamend
core +1 more source
Pathology and Molecular Diagnosis of Marek’s Disease Virus in Chickens in Nigeria
Marek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology, histopathology, and molecular‐based methods.
Olusegun Adesina Fagbohun +12 more
wiley +1 more source
Most of the neoplastic diseases affecting poultry have a viral etiology, such as Marek’s disease, avian leukosis/sarcoma and reticuloendotheliosis. In the present paper, histopathology and molecular methods were performed, in addition of necropsy and ...
M Khordadmehr +3 more
doaj +1 more source
Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. [PDF]
Progenitor cells are considered an important cell of origin of human malignancies. However, there has not been any single gene that can define mammary bipotential progenitor cells, and as such it has not been possible to use genetic methods to introduce ...
Bu, W +10 more
core +2 more sources
Rodent models of tumours of the central nervous system
We describe the evolution of experimental systems, illustrated here in a timeline to show changing popularity over time. Starting with chemical and viral carcinogenesis, systems then developed into increasingly sophisticated genetically modified animal models.
Sebastian Brandner
wiley +1 more source

