Development and Characterization of Monoclonal Antibodies to Subgroup J Avian Leukosis Virus
Avian Diseases, 2001In an attempt to develop a specific diagnostic test for avian leukosis virus (ALV) subgroup J (ALV-J) strain Hc1, four monoclonal antibodies (MAbs), JE9, G2, 145, and J47, were generated that are specific for ALV-J envelope glycoprotein, gp85. Polymerase chain reaction (PCR) was used to amplify genomic pro-viral DNA of Avian Disease and Oncology ...
A, Qin +4 more
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Cardiomyopathy in Broiler Chickens Congenitally Infected with Avian Leukosis Virus Subgroup J
Veterinary Pathology, 2002Dilated cardiomyopathy and ascites in broiler chickens are frequently associated with rapid growth and pulmonary hypertension, but can be associated with some avian leukosis virus (ALV) infections. The novel subgroup J of ALV has a high cardiac tropism, but dilated cardiomyopathy has not been reported previously.
N L, Stedman, T P, Brown
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Detection of Avian Leukosis Virus Subgroup J Using the Polymerase Chain Reaction
Avian Diseases, 1998A polymerase chain reaction (PCR) assay was developed for the detection of avian leukosis virus strain J (ALV-J) in chickens. Primers were based in the E element and the 3' terminus of the long terminal repeat of proviral ALV-J. PCR products were amplified from genomic DNA extracted from chicken embryo fibroblasts (CEF) infected with either strain HPRS-
E J, Smith, S M, Williams, A M, Fadly
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NHE1 gene associated with avian leukosis virus subgroup J infection in chicken
Molecular Biology Reports, 2014As a kind of binding protein, the type 1 Na(+)/H(+) exchanger (NHE1) is a receptor for the highly pathogenic Avian leukosis viruses-J subgroup (ALV-J) in chicken. In order to investigate the potential effect of chicken NHE1 gene on leukosis, we compared its expression between ALV-J-affected and -unaffected chicken, screened variations across the whole ...
Biao, Chen +6 more
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Differential expression of microRNAs in avian leukosis virus subgroup J-induced tumors
Veterinary Microbiology, 2013Avian leukosis virus subgroup J (ALV-J) has become pandemic and induced serious clinical outbreaks in chickens in China. In particular, ALV-J induced various clinical tumors in infected chickens, which caused enormous economic losses to poultry.
Qi, Wang +7 more
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Avian leukosis, caused by avian leukosis virus (ALV), is an infectious tumor disease and severely hinders the development of the poultry industry. The use of Lactobacillus plantarum (L. plantarum) could effectively alleviate viremia in the early period of J subgroup ALV (ALV-J) infection. In this study, an invasive L.
Jing Liu +9 more
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[Cross-species Transmission of Avian Leukosis Virus Subgroup J].
Bing du xue bao = Chinese journal of virology, 2016Avian leukosis virus subgroup J (ALV-J) is an avian retrovirus that can induce myelocytomas. A high-frequency mutation in gene envelope endows ALV-J with the potential for cross-species transmission. We wished to ascertain if the ALV-J can spread across species under selection pressure in susceptible and resistant hosts.
Yanwei, Shen +5 more
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Avian leukosis virus subgroup J: a rapidly evolving group of oncogenic retroviruses
Research in Veterinary Science, 1999A strain of avian leukosis virus (ALV) belonging to a new envelope subgroup J was isolated in the UK in 1988 from meat-type chickens. The disease caused by the members of this subgroup has since spread very rapidly worldwide and has become one of the major problems facing the broiler meat industry. Molecular characterisation of HPRS -103, the prototype
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Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J
Vaccine, 2017Infection with the avian leukosis virus subgroup J (ALV-J) can lead to neoplastic disease in chickens, inflicting significant economic losses to the poultry industry. Recent reports have identified inhibitory effects of ALV-J on autophagy, a process involving in innate and adaptive immunity.
Dai, Zhenkai +9 more
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Geese not susceptible to virulent subgroup J avian leukosis virus isolated from chickens
Avian Pathology, 2019To determine whether geese are susceptible to infection by avian leukosis virus (ALV), 702 serum samples from domestic and foreign goose breeds were screened for p27 antigen as well as being inoculated into DF-1 cell cultures to isolate ALV. Although 5.7% of samples were positive for p27 antigen, reactivity appeared to be non-specific because no ALV ...
Xiaohui, Mu +5 more
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