Results 231 to 240 of about 15,675 (246)

Identification of the Avian Myeloblastosis Virus Genome

1981
In addition to neoplasias caused in chickens by helper viruses of the avian myeloblastosis virus (AMV) complex, acute myeloblastic leukemia is induced by a defective leukemogenic component. To identify the leukemogenic viral genome the unintegrated and integrated viral DNA intermediates were chracterized. Linear viral DNA isolated from the cytoplasm of
D G Bergmann, L M Souza, M A Baluda
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Morphological conversion of cell cultures by avian myeloblastosis virus

Virology, 1961
Abstract There occurs a characteristic morphological conversion when certain cell cultures are infected with avian myeloblastosis virus (AMV). AMV induces the formation of at least two, new and stable, probably neoplastic types of cells—myeloblasts and osteoblasts. The converting effect of AMV upon cell cultures appears to be similar to the oncogenic
M.A. Baluda, I.E. Goetz
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Identification of DNA in the core component of avian myeloblastosis virus

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
Avian myeloblastosis virus (AMV) was found to contain DNA associated with the virion. The viral envelope was removed by treating the virus with a nonionic detergent and the DNA was found in the core fraction. These experiments indicate that the DNA associated with tumor virus is not contaminant associated with the viral envelope and suggest that the ...
G.S. Beaudreau, K. Stromberg, A.O'c. Deeney   +2 more
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Characterization of avian myeloblastosis-associated virus DNA intermediates

Journal of Virology, 1980
The major species of unintegrated linear viral DNA identified in chicken embryonic fibroblasts infected with either the avian myeloblastosis-associated viruses (MAV-1, MAV-2) or the standard avian myeloblastosis virus complex (AMV-S) has a mass of 5.3 X 10(6) daltons. An additional minor DNA component observed only in AMV-S-infected cells has a mass of
M A Baluda, D G Bergmann, L M Souza
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A cryptic transcription promoter in the myb oncogene of avian myeloblastosis virus

Virology, 1986
The potential regulatory signals contained in the v-myb oncogene of avian myeloblastosis virus have been inserted upstream to the herpes simplex type 1 thymidine kinase gene in order to test their promoter activity. The isolation of TK+ transformants after transfection of clone 1D(TK-) mouse cells with the resulting recombinant DNAs indicated that the ...
Janine Crochet, Bernard Perbal, Johann Soret   +2 more
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The binding of polynucleotides to the DNA polymerase of avian myeloblastosis virus

Archives of Biochemistry and Biophysics, 1975
Abstract The interaction between avian myeloblastosis virus DNA polymerase and synthetic nucleic acids was studied by an adaptation of the membrane filter binding technique. Bacillus subtilis DNA was used as a substrate for the binding reaction and was retained on the filters in the presence of the viral polymerase.
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In vivo infectivity studies with avian myeloblastosis virus

Virology, 1961
Abstract Avian myeloblastosis virus (AMV) induces a variety of neoplastic diseases when injected into chicks. A new method of assay of AMV by injection of virus intravenously into 11-day chick embryos is described. This method is more sensitive than injection into newly hatched chicks.
P.P. Jamieson, M.A. Baluda
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VSV Pseudotype Particles with the Coat of Avian Myeloblastosis Virus

Nature New Biology, 1972
PSEUDOTYPES of vesicular stomatitis virus (VSV) with the coat of avian myeloblastosis (AMV) or murine leukaemia viruses—VSV(AMV) and VSV(MLV)—can be produced by growing VSV in chick cells preinfected with AMV or in mouse cells preinfected with MLV1. The VSV particles carrying their own neutralization antigen and double-neutralizable particles may be ...
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Leukemic Transformation with Avian Myeloblastosis Virus: Present Status

1975
Many RNA and DNA tumor viruses induce neoplastic transformation in vitro, but few of these are leukemia viruses acting on hematopoietic target cells. The virus of avian myeloblastosis (AMV) is such an agent, capable of producing morphological changes in hematopoietic tissues grown in vitro, and thus provides an excellent model to study leukemia ...
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Reverse transcriptase from avian myeloblastosis virus: A zinc metalloenzyme

Biochemical and Biophysical Research Communications, 1974
Abstract Previous postulates of a relationship between a zinc enzyme and the leukemic process (1,2) have led to the identification of the RNA dependent DNA polymerase -- reverse transcriptase -- of avian myeloblastosis virus as a zinc metalloenzyme.
Dennis M. Livingston, Bert L. Vallee, H. Kawaguchi, David S. Auld   +3 more
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