Viral Reprogramming of Nucleotide Synthesis and Its Impact on Viral Infection
ABSTRACT Nucleotides are the building blocks of DNA and RNA. They also play essential roles in various other biological processes, including protein glycosylation, ribosome biogenesis, and cytoskeletal function. The significance of the regulation of nucleotide metabolism has recently gained more attention in many physiological and pathological contexts,
Lara Dsouza, Zhilong Yang
wiley +1 more source
Identification of an avian polyomavirus associated with Adélie penguins (Pygoscelis adeliae) [PDF]
Little is known about viruses associated with Antarctic animals, although they are probably widespread. We recovered a novel polyomavirus from Adélie penguin (Pygoscelis adeliae) faecal matter sampled in a subcolony at Cape Royds, Ross Island, Antarctica.
Julian, Laurel +8 more
core +3 more sources
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source
Disease screening of three breeding populations of adult exhibition budgerigars (Melopsittacus undulatus) in New Zealand reveals a high prevalence of a novel polyomavirus and avian malaria infection [PDF]
Disease surveillance is vital to the management of New Zealand’s endemic and threatened avian species. Three infectious agents that are potential threats to New Zealand’s endemic birds include avian polyomavirus (APV), beak and feather disease virus ...
Baron, Hamish R. +7 more
core +1 more source
Abstract Zoonoses constitute a major risk to human health. Comprehensive assessments on the potential emergence of novel disease outbreaks are essential to ensure the effectiveness of sanitary controls and to establish mitigating actions. Through a continental‐scale survey of rural human settlements conducted over 13 years in 15 Neotropical countries ...
Pedro Romero‐Vidal +10 more
wiley +1 more source
Mesenchymal stem cell therapy in diabetic foot ulcer: An updated comprehensive review
Abstract Background Diabetes has evolved into a worldwide public health issue. One of the most serious complications of diabetes is diabetic foot ulcer (DFU), which frequently creates a significant financial strain on patients and lowers their quality of life.
Helal F. Hetta +9 more
wiley +1 more source
Phylogenetic analysis of caribou polyomavirus.
PhyML tree with LG and 100 bootstrap replicates of a fragment of the large T antigen of caribou polyomavirus from the nose swab of animal 20 and various viruses of the family Polyomaviridae (corresponding to large T antigen amino acids 305 to 390 of ...
Debby Schipper (619086) +10 more
core +1 more source
In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]
During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
core +1 more source
Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy
Abstract Cancer is a leading cause of death worldwide. Targeted therapies aimed at key oncogenic driver mutations in combination with chemotherapy and radiotherapy as well as immunotherapy have benefited cancer patients considerably. Tumor protein p53 (TP53), a crucial tumor suppressor gene encoding p53, regulates numerous downstream genes and cellular
Bin Song, Ping Yang, Shuyu Zhang
wiley +1 more source
Getah Virus: A New Contaminant in Veterinary Vaccines
Mycoplasma, reticuloendotheliosis virus (REV), avian leukosis virus (ALV), chicken infectious anemia virus (CIAV), bovine polyomavirus (BPV), bovine viral diarrhea virus (BVDV), and porcine circovirus (PCV) are considered common contaminants in live ...
Pin-Pin Chu +4 more
doaj +1 more source

