Results 91 to 100 of about 1,393,402 (283)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Perceived control and avoidance in posttraumatic stress
European Journal of Psychotraumatology, 2018 Despite much evidence concerning the importance of control over stressors in animal models of adaptation to stress, there is a dearth of experimental evidence for the role of controllability in posttraumatic stress disorder (PTSD).
Lisa Hancock, Richard A. Bryant
doaj +1 more source
Frontiers in Psychology, 2018 Abundant evidence suggests that affective stimuli facilitate responses that lead to a compatible change in distance between the affective stimulus and the self (positive → approach, negative → avoidance). A special situation arises, when a barrier blocks
Regina Reichardt
doaj +1 more source
Avoided intersections of nodal lines
, 2002 We consider real eigen-functions of the Schr\"odinger operator in 2-d. The nodal lines of separable systems form a regular grid, and the number of nodal crossings equals the number of nodal domains.
Alejandro G Monastra +14 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Decision making and behavioral choice during predator avoidance
Frontiers in Neuroscience, 2012 One of the most important decisions animals have to make is how to respond to an attack from a potential predator. The response must be prompt and appropriate to ensure survival.
Jens eHerberholz, Gregory D Marquart
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Retrosplenial cortex and aversive conditioning
Frontiers in Behavioral NeuroscienceThe retrosplenial cortex (RSC) is well-known for its contribution to episodic memory, as well as contextual and spatial learning and memory. However, two literatures have also emerged examining the role of the RSC in aversive conditioning. The purpose of
Han Yin Cheng +2 more
doaj +1 more source
Frontiers in Psychology, 2015 Within the literature on emotion and behavioral action, studies on approach-avoidance take up a prominent place. Several experimental paradigms feature successful conceptual replications but many original studies have not yet been replicated directly. We
Mark eRotteveel +14 more
doaj +1 more source
PENGARUH CAPITAL INTENSITY, CORPORATE SOCIAL RESPONSIBILITY (CSR), DAN FINANCIAL DISTRESS TERHADAP PENGHINDARAN PAJAK (TAX AVOIDANCE) [PDF]
Tax avoidance is a tax avoidance strategy and technique that is carried out legally and safely because it does not conflict with tax provisions. The methods and techniques used are by exploiting weaknesses (gray areas) contained in the tax laws and ...
Budiman, Farah Fauziah
core