Results 51 to 60 of about 6,614,549 (286)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Avoidance Learning Using Observational Reinforcement Learning

CoRR, 2019
Imitation learning seeks to learn an expert policy from sampled demonstrations. However, in the real world, it is often difficult to find a perfect expert and avoiding dangerous behaviors becomes relevant for safety reasons. We present the idea of \textit{learning to avoid}, an objective opposite to imitation learning in some sense, where an agent ...
David Venuto, Léonard Boussioux, Junhao Wang, Rola Dali, Jhelum Chakravorty, Yoshua Bengio, Doina Precup   +6 more
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Disgust as an adaptive system for disease avoidance behaviour. [PDF]

, 2011
Disgust is an evolved psychological system for protecting organisms from infection through disease avoidant behaviour. This 'behavioural immune system', present in a diverse array of species, exhibits universal features that orchestrate hygienic ...
Aunger, Robert, Robert Aunger, Valerie Curtis, de Barra, Mícheál, Curtis, Valerie, Mícheál de Barra   +5 more
core   +1 more source

Avoidance Learning: A Review of Theoretical Models and Recent Developments

Frontiers in Behavioral Neuroscience, 2015
Avoidance is a key characteristic of adaptive and maladaptive fear. Here, we review past andcontemporary theories of avoidance learning. Based on the theories, experimental findings and clinical observations reviewed, we distil key principles of how ...
Angelos-Miltiadis eKrypotos, Angelos-Miltiadis eKrypotos, Marieke eEffting, Marieke eEffting, Merel eKindt, Merel eKindt, Tom eBeckers, Tom eBeckers, Tom eBeckers   +8 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Learning Barrier-Certified Polynomial Dynamical Systems for Obstacle Avoidance with Robots [PDF]

Established techniques that enable robots to learn from demonstrations are based on learning a stable dynamical system (DS). To increase the robots\u27 resilience to perturbations during tasks that involve static obstacle avoidance, we propose ...
Kussaba, Hugo T. M., Swikir, Abdalla, Billard, Aude, Chen, Lingyun, Haddadin, Sami, Figueredo, Luis, Schonger, Martin   +6 more
core   +1 more source

Generalization of socially transmitted and instructed avoidance

Frontiers in Behavioral Neuroscience, 2015
Excessive avoidance behavior, in which an instrumental action prevents an upcoming aversive event, is a defining feature of anxiety disorders. Left unchecked, both fear and avoidance of potentially threatening stimuli may generalize to perceptually ...
Gemma eCameron, Gemma eCameron, Michael W Schlund, Simon eDymond   +3 more
doaj   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

The Effect of Early Mobilization Programs on the Heart-focused Anxiety in Patients with Acute Myocardial Infarction: A Randomized Clinical Trial

Iranian Journal of Nursing and Midwifery Research
Background: Early Mobilization (EM) after a myocardial infarction is an effective strategy to reduce complications associated with immobility. However, heart-focused anxiety (HFA) can hinder exercise capacity and negatively impact self-reported physical ...
Reihane Askari, Ahmadreza Yazdannik, Iraj Shams, Masoomeh Goodarzi-Khoigani   +3 more
doaj   +1 more source