Dexmedetomidine as adjunct in awake craniotomy – improvement or not?
BackgroundOver the last decade, awake craniotomy for tumor resection has become a standard to maximize tumor resection and minimize the risk of permanent neurological deficits. Different techniques and medication regimes have been tested for this procedure. Until today there is no consensus on the optimal approach. Therefore, we investigated the effect
Elisabeth H Adam+5 more
openaire +3 more sources
Changes in cortical delta power during chronic invasive epilepsy monitoring
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen+4 more
wiley +1 more source
Effects on Breathing of Agonists to μ-opioid or GABA\u3csub\u3eA\u3c/sub\u3e Receptors Dialyzed into the Ventral Respiratory Column of Awake and Sleeping Goats [PDF]
Pulmonary ventilation (V̇I) in awake and sleeping goats does not change when antagonists to several excitatory G protein-coupled receptors are dialyzed unilaterally into the ventral respiratory column (VRC).
Burgraff, Nicholas J.+7 more
core +1 more source
Anesthetic management in awake craniotomy [PDF]
Resection of brain tumors may cause neurological sequelae, according to the site and size of the brain tissue removed. Awake craniotomy has been proposed as a surgical approach to satisfy criteria of radical surgery while minimizing eloquent brain damage.
AMATO DE MONTE+5 more
core +2 more sources
Anaesthetic technique during awake craniotomy. Case report and literature review
Introduction: Awake craniotomy for neurostimulation can be managed with different anaesthetic techniques, ranging from local anaesthesia or local anaesthesia with sedation to intermittent general anaesthesia. Materials and methods: We present the case of
M.M. Madriz-Godoy, S.A. Trejo-Gallegos
doaj +1 more source
Patient Selection for Awake Craniotomy <Patient Selection, Awake Craniotomy>
The first awake craniotomy (AC) applications were found in archaeological excavations in Peru. The successful healing rate was 55% of trephinations in 214 skulls. Coca leaves were used as a local anesthetic before the general anesthesia (GA) era. The first recorded case of AC was the epilepsy surgery performed by Sir Victor Horsley in 1886 [1].
Yakar, F., Coşkun, M.E.
openaire +2 more sources
Tumor‐related epilepsy in glioma: A multidisciplinary overview
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci+29 more
wiley +1 more source
Abstract figure legend Here, we find that GluN2D‐containing NMDA receptors (NMDARs) are expressed by most vasoactive intestinal peptide neurons in the inferior colliculus (IC). These receptors are less susceptible to Mg2+ blockade compared to GluN2A/B‐containing NMDARs, allowing ions to flow at resting membrane potential.
Audrey C. Drotos+3 more
wiley +1 more source
A case of failed awake craniotomy due to progressive intraoperative hyponatremia
Background Perioperative seizure control is correlated with a better surgical outcome for awake craniotomy, but some anticonvulsants can induce hyponatremia. Mannitol has also been reported to be hyponatremic. Case presentation A 51-year-old right-handed
Suguru Yamamoto+4 more
doaj +1 more source
Characterizing optogenetically mediated rebound effects in anaesthetized mouse primary visual cortex
Abstract figure legend Many studies of cortical circuits use optogenetic activation of inhibitory interneurons to suppress pyramidal cell activity, but after the light is turned off pyramidal cells sometimes show excess spiking, which is called a post‐inhibitory rebound.
Jared T. Shapiro+2 more
wiley +1 more source