Impaired perceptual learning in a mouse model of Fragile X syndrome is mediated by parvalbumin neuron dysfunction and is reversible. [PDF]
To uncover the circuit-level alterations that underlie atypical sensory processing associated with autism, we adopted a symptom-to-circuit approach in the Fmr1-knockout (Fmr1-/-) mouse model of Fragile X syndrome.
A Contractor +53 more
core +2 more sources
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han +17 more
wiley +1 more source
An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]
Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver +6 more
core +2 more sources
The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller +3 more
wiley +1 more source
A case of failed awake craniotomy due to progressive intraoperative hyponatremia
Background Perioperative seizure control is correlated with a better surgical outcome for awake craniotomy, but some anticonvulsants can induce hyponatremia. Mannitol has also been reported to be hyponatremic. Case presentation A 51-year-old right-handed
Suguru Yamamoto +4 more
doaj +1 more source
Effects on Breathing of Agonists to μ-opioid or GABA\u3csub\u3eA\u3c/sub\u3e Receptors Dialyzed into the Ventral Respiratory Column of Awake and Sleeping Goats [PDF]
Pulmonary ventilation (V̇I) in awake and sleeping goats does not change when antagonists to several excitatory G protein-coupled receptors are dialyzed unilaterally into the ventral respiratory column (VRC).
Burgraff, Nicholas J. +7 more
core +1 more source
Entropy-guided use of a unique cocktail in awake craniotomy
The major benefit of awake craniotomy is to enable a tailored resection that can theoretically maximize the extent of the tumor resection and can minimize the neurological damages. There is still no consensus as to the best anesthetic technique.
Itee Chowdhury +3 more
doaj +1 more source
Subtype-specific plasticity of inhibitory circuits in motor cortex during motor learning. [PDF]
Motor skill learning induces long-lasting reorganization of dendritic spines, principal sites of excitatory synapses, in the motor cortex. However, mechanisms that regulate these excitatory synaptic changes remain poorly understood.
Chen, Simon X +3 more
core
PERANAN PAKAR BIUS AMAT PENTING DALAM PROSEDUR PEMBEDAHAN [PDF]
KUBANG KERIAN, KELANTAN, 18 Januari 2017 - Seringkali kejayaan sesuatu pembedahan digambarkan dengan kehebatan pakar bedah yang melaksanakan pembedahan tersebut.
MPRC, Pusat Media & Perhubungan Awam
core
Preliminary study of awake craniotomy in the treatment of recurrent gliomas in eloquent areas
Objective To investigate the feasibility, efficacy and safety of awake craniotomy with brain functional mapping for the interoperative resection of recurrent gliomas in eloquent areas.
YAO Shu⁃jing +5 more
doaj +1 more source

