Results 281 to 290 of about 175,387 (374)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Indo-US Emergency and Trauma Collaborative Clinico-pathologic Case Competitions Celebrate 20 Years of Competitive Educational Learning Experience.

J Emerg Trauma Shock
Aggarwal P, Galwankar S, Sardesai I, Soghoian S, Wiener SW.   +4 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

"Best Paper" awards lack transparency, inclusivity, and support for Open Science. [PDF]

PLoS Biol
Lagisz M, Rutkowska J, Aich U, Ross RM, Santana MS, Wang J, Trubanová N, Page MJ, Pua AAY, Yang Y, Amin B, Martinig AR, Barnett A, Surendran A, Zhang J, Borg DN, Elisee J, Wrightson JG, Nakagawa S.   +18 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Disparities in funding for Nobel Prize awards in medicine and physiology across nationalities, races, and gender. [PDF]

J Cell Physiol
Neikirk K, Vue Z, Vue N, Barongan T, Vang C, Beasley HK, Marshall AG, Kirabo A, Wanajalla CN, Smith N, Morton D, Shuler HD, Hinton A.   +12 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

An open chat with…Pierre Santucci: a testimonial on why we should engage with scientific societies and their journals. [PDF]

FEBS Open Bio
Santucci P, Tsagakis I.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Gender disparities in social and personality psychology awards from 1968 to 2021. [PDF]

Commun Psychol
Hopkins-Doyle A, Chalmers J, Toribio-Flórez D, Cichocka A.   +3 more
europepmc   +1 more source