Results 41 to 50 of about 291,043 (296)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The conversation: developing confidence to provide end of life care in Salford nursing homes [PDF]

open access: yes, 2011
The study was funded by the Burdett Trust for Nursing and partly by Salford Primary Care Trust. A realistic evaluation design was used to collect data using a range of approaches, from before and after surveys of confidence in delivering end of life care,
Attree, M   +4 more
core  

Determination of the Topology of a Directed Network

open access: yes, 2002
We consider strongly-connected directed networks of identical synchronous, finite-state processors with in- and out-degree uniformly bounded by a network constant.
Goldstein, Darin
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Learning end-of-life care within a constructivist model: Undergraduate nursing students’ experiences

open access: yesCurationis, 2015
Background: Although nursing education aims to equip nursing students to provide care to dying patients and their families, nurses often feel ill-prepared to cope with the emotional labour involved in end-of-life care.
Anna E. van der Wath, Pieter H. du Toit
doaj   +1 more source

Beautiful Deaths and Heard Gazes

open access: yesEikón Imago, 2021
Viewers frequently encounter “normative” prescriptions and perceptions through photographs of how images depicting death and dying should loo and, cognitively, how those images ought to be received.
David Staton
doaj   +1 more source

The Experiences of Gay, Lesbian, Bisexual and Transgender People around End-of-Life Care [PDF]

open access: yes, 2010
All States and Territories in Australia have implemented legislation relating to end-of-life decision-making and substitute judgment. However, reports to relevant legal and community services indicate that many gay, lesbian, bisexual and transgender ...
Colleen Cartwright   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Excellent Dyeing Properties of a Natural Dye Extracted from the Leaves of Phoenix dactylifera Linn on Cotton and Silk Fabrics

open access: yesJournal of Natural Fibers, 2022
There has been recently a worldwide interest in the production and application of natural dyes due to the growing awareness about cleaner surroundings and healthy lifestyle.
Shahin Hossain   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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