Results 91 to 100 of about 2,349,133 (334)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Nanometric axial localization of single fluorescent molecules with modulated excitation
Distance measurements are commonly performed by phase detection based on a lock-in strategy. Super-resolution fluorescence microscopy is still striving to perform axial localization but through entirely different strategies.
P. Jouchet +6 more
semanticscholar +1 more source
Bubble-Driven Inertial Micropump
The fundamental action of the bubble-driven inertial micropump is investigated. The pump has no moving parts and consists of a thermal resistor placed asymmetrically within a straight channel connecting two reservoirs.
Alexander N. Govyadinov +7 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
It is possible to increase the efficacy of herbicides by adding vegetable oils to the spray tank. In order to evaluate and study this fact a greenhouse study was conducted.
Mehdi Rastgoo +2 more
doaj
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Predicting the behaviour of plastic hinges subjected to large inelastic deformations caused by extreme loads such as earthquakes plays an important role in assessing maximum stable deformation capacities of framed concrete structures. This paper presents
Jacek Korentz
doaj +1 more source
Chiral Corrections to Hyperon Axial Form Factors
We study the complete set of flavor changing hyperon axial current matrix elements at small momentum transfer. Using partially quenched heavy baryon chiral perturbation theory, we derive the chiral and momentum behavior of the axial and induced ...
B. Borasoy +3 more
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source

