Results 121 to 130 of about 2,349,133 (334)

Guías argentinas de práctica clínica, diagnóstico, evaluación y tratamiento en pacientes adultos con espondiloartritis axial

Revista Argentina de Reumatología
La espondiloartritis axial (EspAax) es una enfermedad crónica inflamatoria que incluye a la espondiloartritis radiográfica (EspAax-r) (anteriormente conocida como espondilitis anquilosante [EA]) y a la espondiloartritis axial no radiográfica (EspAax-nr)
María Victoria Martire, Mariana Benegas, Carla Airoldi, Natalia Zamora, Gustavo Citera, Enrique Soriano, Emilio Buschiazzo, Dafne Capelusnik, Tomás Cazenave, Vanesa Cosentino, Leandro Ferreyra Garrot, Rodrigo García Salinas, Carolina Isnardi, Maximiliano Machado Escobar, José Maldonado Cocco, Hernán Maldonado Fico, Josefina Marin, Romina Nieto, Rodolfo Pérez Alamino, Javier Eduardo Rosa, Fernando Sommerfleck, Diego Vila, Diana Fernández, Emilce E. Schneeberger   +23 more
doaj   +1 more source

Gota axial

Revista Brasileira de Reumatologia, 2013
A gota axial pode afetar todos os segmentos da coluna vertebral. Ela se manifesta como dor nas costas, dor associada com sintomas neurológicos, e como comprometimento neurológico sem dor em 17,9%, 75,8% e 4,2% dos casos, respectivamente.
Eduardo Massato Hasegawa, Filipe Martins de Mello, Cláudia Goldenstein-Schainberg, Ricardo Fuller   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Weak axial nuclear heavy meson exchange currents and interactions of solar neutrinos with deuterons

, 2007
Starting from the axial heavy meson exchange currents, constructed earlier in conjunction with the Bethe--Salpeter equation, we first present the axial $\rho$--, $\omega$-- and $a_1$ meson exchange Feynman amplitudes that satisfy the partial conservation
Adam, Adam, Adam, Adam, Adam, Adler, Aharmin, Akram, Ananyan, Ananyan, Ando, Ando, B. Mosconi, Balantekin, Bando, Bergervoet, Bernard, Bijnens, Blatt, Blin-Stoyle, Blucher, Butler, Butler, Butler, Callan, Carlson, Carlson, Chang, Chemtob, Ciechanowicz, Coester, Coleman, Congleton, Davidson, De Alfaro, de Téramond, Diaconescu, Dmitrašinović, Dobaczewski, Dogotar, Donoghue, E. Truhlík, Eidelman, Ericson, Friar, Frois, Fuchs, Gasiorowicz, Gasser, Gasser, Gell-Mann, Gilman, Gorringe, Guichon, Göller, Hadjimichel, Hemmert, Hirschi, Hošek, Hwang, Hwang, Ivanov, Ivanov, Ivanov, Jaus, Jäger, Kaplan, Kaplan, Khanna, Kirchbach, Kirchbach, Kubodera, Kubodera, Küster, Lee, Machleidt, Machleidt, Machleidt, Marciano, Marcucci, Marcucci, Mathiot, Measday, Meissner, Meissner, Meissner, Mosconi, Mosconi, Mosconi, Mosconi, Nakamura, Nakamura, Nozawa, O'Connell, Obersteiner, Ogievetsky, P. Ricci, Park, Park, Park, Park, Park, Pascalutsa, Poon, Poulis, Rho, Rho, Riska, Riska, Saito, Sakurai, Savage, Schiavilla, Schwinger, Schwinger, Sick, Smejkal, Smejkal, Smejkal, Stoks, Tatara, Towner, Towner, Towner, Truhlík, Truhlík, Tsushima, Walecka, Walecka, Warburton, Warburton, Weinberg, Weinberg, Weinberg, Wess, Wiringa, Ying   +136 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Influence of laser spot size at diffuser plane on the longitudinal spatial coherence function of optical coherence microscopy system

, 2019
Coherence properties and wavelength of light sources are indispensable for optical coherence microscopy/tomography as they greatly influence the signal to noise ratio, axial resolution, and penetration depth of the system.
Ahmad, Azeem, Butola, Ankit, Dubey, Vishesh, Joshi, Rakesh, Mehta, Dalip Singh, Usmani, Kashif   +5 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Axial osteomalacia [PDF]

Postgraduate Medical Journal, 1971
J R, Condon, J R, Nassim
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source