Results 201 to 210 of about 48,227 (268)

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

Posterolateral Tibial Plateau Fractures-Does Fixation Choice Matter? A Biomechanical Investigation. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Chailertpongsa P, Donnimitsakul S, Laonapakul T, Samrid R, Thienthong K, Twinprai N, Sripadungkul S, Phruetthiphat OA, Apinyankul R.   +8 more
europepmc   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Study on fracture propagation and evolution characteristics of coal samples under uniaxial compression. [PDF]

Sci Rep
Weibin G, Jiahao Z, Yuhui L, Gang W, Yichen G.   +4 more
europepmc   +1 more source

Spontaneous Helical Alignment of Smooth Muscle Cells to Form a Medial Layer for Engineered Microvasculature

Advanced Healthcare Materials, EarlyView.
Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest, Katherine J. Young, Isabella K. Holtz, Mark Mc Veigh, James D. West, Leon M. Bellan   +5 more
wiley   +1 more source

Assessing PHILOS plate as an alternative fixation method for pediatric femoral neck fractures: a biomechanical comparison with cannulated screws. [PDF]

Arch Orthop Trauma Surg
Lim BS, Wang YP, Chung ST, Wang CH, Chang SW, Wang TM, Hong CK.   +6 more
europepmc   +1 more source

A New Type of High-Sensitivity Fiber Grating Pressure Sensor. [PDF]

Sensors (Basel)
Li WC, Liu WF.
europepmc   +1 more source

Development of 3D-Printed Cementitious Layered Model Rocks with Recycled Waste: A Study on Anisotropy. [PDF]

Materials (Basel)
Hu Y, Wang Y, Wang Z, Wang S, Hu J, Wang L, Xu X.   +6 more
europepmc   +1 more source