Results 61 to 70 of about 29,865 (265)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Cone mosaic in eyes with varied axial length using adaptive optics scanning laser ophthalmoscopy
Photodiagnosis and Photodynamic TherapyBackground: Abnormalities in cone photoreceptor topography are closely associated with the development of various ocular diseases, including axial myopia.
Wen-Da Zhou +11 more
doaj +1 more source
Results in Physics, 2016 In this article magnetized plasma filled traveling wave tubes are investigated. The mentioned system, is located inside a cylindrical wall. The space between the helix and the wall is filled with dielectric material.
M. Shaban, A. Baharvand, S. Saviz
doaj +1 more source
Fabrication and analysis of mechanical properties of PVC/Glass fiber/graphene nano composite pipes
Materials Research Express, 2020 The aim of this work is to examine the conventional moulding method for manufacturing the PVC/Glass fiber/graphene nano composites. Uniform graphene dispersion is observed with the matrix for better bonding.
G Shanmugasundar +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Liquid-Phase Back mixing in Bubble Columns
Tikrit Journal of Engineering Sciences, 2013 Liquid-phase axial dispersion coefficients have been measured for air-water system in bubble columns of 10, 15 and 30 cm diameter. The experiments are carried out using a transient method (the tracer response method).
Burhan S. Abdulrazak
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Guided Waves in a Solid Rod Embedded in Infinite Medium with Weak Interface
MATEC Web of Conferences, 2016 The dispersion relation of the infinite long rod model with a weak interface has been deduced via wave equation of the guided waves and boundary spring interface model.
Tong Zi Wei +5 more
doaj +1 more source
Photonics, 2014 A study of the effect of temperature and axial strain on the parametric wavelengths produced by four-wave mixing in microstructured optical fibers is presented. Degenerate four-wave mixing was generated in the fibers by pumping at normal dispersion, near
Javier Abreu-Afonso +3 more
doaj +1 more source