Results 61 to 70 of about 893,699 (299)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
GAS HOLDUP AND AXIAL LIQUID DISPERSION IN THREE PHASE BUBBLE COLUMNS
Journal of Engineering and Sustainable Development, 2015 Axial liquid dispersion coefficient was studied in air-tap water systems (bubble columns) and air-tap water-PVC solid particles systems for different column diameters, 10, 15, and 30 cm, Each column had a gas distributor plate with perforated holes of
Burhan Sadeq Abdulrazzaq
doaj
Axial mixing with spiral-shaped channel micromixer
Journal of Fluid Science and Technology, 2015 Axial fluctuations in carrier concentrations cause detection noise during chemical analysis using flowing carrier streams. Here, we report a method of axial mixing using serially cascaded microchannel units with branches and junctions.
Nobuhiro TSUKADA +2 more
doaj +1 more source
Hyperbolic axial dispersion model [PDF]
, 2012 Axial dispersion model is most reliable tool for analyzing the transient response of flow system inside a bundle of pipes. The proposed hyperbolic model considers propagation velocity of flow disturbance to be finite and even of the order of flow ...
Dalai, Radharaman
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Study the Axail Dispersion Model in Ion Exchange Column
Al-Khawarizmi Engineering Journal, 2009 A mathematical model is developed which predicates the performance of cylindrical ion exchange bed involving comparing of axial dispersion model for cation exchange column with different assumption, this model permits the performance to predicate the ...
Iman Hahider Mahdi
doaj +2 more sources
Axial dispersion of the liquid phase in vertical tubular contactors with static mixers
, 1986 Axial dispersion characteristics in the liquid phase have been determined for three selected types of static mixers using the impulse response technique in a vertical tubular contactor for single phase (water) and two phase (water-air, cocurrent flow ...
Marie Fialová +2 more
core +1 more source