Results 61 to 70 of about 1,497,791 (338)

Investigation by laser doppler velocimetry of the effects of liquid flow rates and feed positions on the flow patterns induced in a stirred tank by an axial-flow impeller [PDF]

open access: yes, 2002
The (ow patterns established in a continuously-fed stirred tank, equipped with a Mixel TT axial-(ow impeller, have been investigated bylaser Doppler velocimetry, for a high and a low value of mean residence time—mixing time ratio.
Mavros, Paul   +3 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

CFD analysis of industrial multi-staged stirred vessels [PDF]

open access: yes, 2006
This paper presents tools for analysis of CFD results adapted for flows in multi-stage stirred vessels through out two industrial cases. Those tanks fitted with double-flow impellers are used first to cool down highly viscous resins and subsequently for ...
Philippe Hobbes   +12 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

GAS HOLDUP AND AXIAL LIQUID DISPERSION IN THREE PHASE BUBBLE COLUMNS

open access: yesJournal of Engineering and Sustainable Development, 2015
Axial liquid dispersion coefficient was studied in air-tap water systems (bubble columns) and air-tap water-PVC solid particles systems for different column diameters, 10, 15, and 30 cm, Each column had a gas distributor plate with perforated holes of
Burhan Sadeq Abdulrazzaq
doaj  

Axial mixing with spiral-shaped channel micromixer

open access: yesJournal of Fluid Science and Technology, 2015
Axial fluctuations in carrier concentrations cause detection noise during chemical analysis using flowing carrier streams. Here, we report a method of axial mixing using serially cascaded microchannel units with branches and junctions.
Nobuhiro TSUKADA   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Axial Dispersion in Gas-Bubble Columns

open access: yesChemical engineering, 1971
本研究では前報の流動モデルの理論を拡張し, 循環速度分布の存在は平均流方向での混合となることに基づいて, Taylor, Ticha・cekらによって論じられた速度分布モデルを適用し, 気泡塔装置の乱流域における軸方向混合拡散についての理論式を導いた。この結果に対し, 前報で得られた実験式を導入して, 気泡塔への適用を試みた。総括の混合拡散係数を, 平均循環速度と塔径基準のPe数で表現し, また, 混合拡散に対するガス空塔速度と塔径の影響を示す相関式を導いた。
Shyu, Chia-San, Miyauchi, Terukatau
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Study the Axail Dispersion Model in Ion Exchange Column

open access: yesAl-Khawarizmi Engineering Journal, 2009
A mathematical model is developed which predicates the performance of cylindrical ion exchange bed involving comparing of axial dispersion model for cation exchange column with different assumption, this model permits the performance to predicate the ...
Iman Hahider Mahdi
doaj   +2 more sources

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