Results 41 to 50 of about 29,857 (265)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reactive solute transport in blood flow through a permeable capillary

open access: yesArchives of Mechanics, 2022
The present analysis discusses the solute transport process in a steady 2D (axial and radial) laminar flow of blood through a permeable, finite length capillary.
S. Debnath, A.K. Roy, O.A. Bég
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Axial Dispersion in Gas-Bubble Columns

open access: yesChemical engineering, 1971
本研究では前報の流動モデルの理論を拡張し, 循環速度分布の存在は平均流方向での混合となることに基づいて, Taylor, Ticha・cekらによって論じられた速度分布モデルを適用し, 気泡塔装置の乱流域における軸方向混合拡散についての理論式を導いた。この結果に対し, 前報で得られた実験式を導入して, 気泡塔への適用を試みた。総括の混合拡散係数を, 平均循環速度と塔径基準のPe数で表現し, また, 混合拡散に対するガス空塔速度と塔径の影響を示す相関式を導いた。
Shyu, Chia-San, Miyauchi, Terukatau
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Axial dispersion-managed liquid-core fibers: A platform for tailored higher-order mode supercontinuum generation

open access: yesAPL Photonics, 2022
Soliton-based supercontinuum generation is a powerful approach for generating light with the desired properties, although limited dispersion tuning capabilities remain a key challenge.
Xue Qi   +5 more
doaj   +1 more source

DISPERSION IN A TWO-PHASE FLOW SULZER COLUMN

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2023
An experimental study based on the pulse-response technique was performed in a Sulzer packed-bed column in order to establish the residence time distribution for four different liquid flow rates, namely 200, 400, 600 and 800 L/h and five different gas ...
Eugenia Teodora IACOB TUDOSE
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Application of transfer function for quick estimation of gas flow parameters—A useful model‐based approach to enhancing measurements

open access: yesEngineering Reports, 2021
At the core of chemical engineering, process design is fundamental to reach a goal of productivity. Axial dispersion is one of the key phenomena that can affect productivity.
Mirosław K. Szukiewicz, Adrian Szałek
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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