Results 121 to 130 of about 893,699 (299)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Oscillatory flow and axial dispersion in packed beds of spheres
, 2016 The effect of oscillations in the bulk flow on the axial dispersion coefficient in packed beds of spherical particles has been studied using the imperfect pulse tracer method with two probes located within the bed.
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Dispersion analysis of an acidogenic UASB reactor
, 2008 The dispersion behavior of an upflow anaerobic sludge blanket (UASB) reactor for acidogenesis was investigated, and its flow patterns were simulated. Compared with the single-zone axial-dispersion model (with squared difference from 130 to 450), a two ...
Yu, Han-Qing +4 more
core +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Response of a Reactor with Axial Dispersion to a Pulse Input Tracer (E-Curve)
, 2014 One needs basic knowledge about chemical reactionsA reactor with axial dispersion is given. One can analise the concentration rate of this reactionComponente Curricular::Educação Superior::Ciências Exatas e da Terra ...
Binous, Housam
core
Axial dispersion in segmented gas-liquid flow: Effects of alternating channel curvature
, 2010 The effects of channel curvature on the axial dispersion in segmented gas-liquid flows are studied computationally in a two-dimensional setting using a finite-volume/front-tracking method.
Metin Muradoglu, Muradoglu, Metin
core +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source