Results 41 to 50 of about 833,436 (305)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Generalized semi-opened axial dispersion model [PDF]
, 2012 The axial dispersion model (ADM) is studied and then generalized by a new form of the left boundary condition of semi-open flow system. The resulting parameter driven model covers the traditional axial models: axial closed-opened dispersion model with ...
Jakeš, B., Kukal, J., Bártová, D.
core
Residence time distribution measurements in an external-loop airlift reactor: Study of the hydrodynamics of the liquid circulation induced by the hydrogen bubbles [PDF]
, 2011 A detailed study of the residence time distribution (RTD) analysis of liquid phase has been performed in an external-loop airlift reactor of 20 L nominal volume, regarded as a global unit and discriminating its different sections (riser, gas–liquid ...
A.H. Essadki +7 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Flow and axial dispersion simulation for traveling axisymmetric Taylor vortices
, 1998 Numerical experiments using a finite difference method were carried out to determine the motion of axisymmetric Taylor vortices for narrow-gap Taylor vortex flow.
Rudman, M, Howes, T
core +1 more source
Reactive solute transport in blood flow through a permeable capillary
Archives of Mechanics, 2022 The present analysis discusses the solute transport process in a steady 2D (axial and radial) laminar flow of blood through a permeable, finite length capillary.
S. Debnath, A.K. Roy, O.A. Bég
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
APL Photonics, 2022 Soliton-based supercontinuum generation is a powerful approach for generating light with the desired properties, although limited dispersion tuning capabilities remain a key challenge.
Xue Qi +5 more
doaj +1 more source
DISPERSION IN A TWO-PHASE FLOW SULZER COLUMN
Studia Universitatis Babes-Bolyai Chemia, 2023 An experimental study based on the pulse-response technique was performed in a Sulzer packed-bed column in order to establish the residence time distribution for four different liquid flow rates, namely 200, 400, 600 and 800 L/h and five different gas ...
Eugenia Teodora IACOB TUDOSE
doaj +1 more source