Results 91 to 100 of about 1,854,799 (291)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Solute dispersion in a permeable capillary with wall exchange: Darcy flow model [PDF]

Complex chemical reactions and hydrodynamic dispersion feature in many aspects of hemodynamics. Motivated by examining the reactive phase change dispersion in perfusion, a mathematical study is presented for solute dispersion in incompressible laminar ...
Shaw, Sachin, Anwar Bég, O, Kumar, Ashis, Bég, Tasveer A, Mashiku, Lazaro Revocatus   +4 more
core  

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Studies of Adsorption of Heavy Metals onto Spent Coffee Ground: Equilibrium, Regeneration, and Dynamic Performance in a Fixed-Bed Column

International Journal of Chemical Engineering, 2016
Equilibrium and dynamic adsorption of heavy metals onto spent coffee ground (SCG) were studied. The equilibrium adsorption of Cd2+, Cu2+, and Pb2+ in a batch system was modeled by an ion-exchange model (IEM) based on an ion-exchange of heavy metals with ...
N. E. Davila-Guzman, F. J. Cerino-Córdova, M. Loredo-Cancino, J. R. Rangel-Mendez, R. Gómez-González, E. Soto-Regalado   +5 more
doaj   +1 more source

Modeling of protein breakthrough performance in cryogel columns by taking into account the overall axial dispersion.

, 2009
A model considering the overall axial dispersion for describing protein adsorption and breakthrough in monolithic cryogel beds has been developed.
Junxian Yun, Bo Mattiasson, Yun, Junxian, Kirsebom, Harald, Galaev, Igor, Mattiasson, Bo, Igor Yu Galaev, Harald Kirsebom   +7 more
core   +1 more source

Significance of axial heat dispersion for the description of heat transport in wall-cooled packed beds [PDF]

, 1992
two-dimensional pseudo-homogeneous model with axial dispersion of heat has been solved numerically with different boundary conditions at the inlet and outlet of the packed bed.
Borkink, J.G.H., Borkink, J.G. Harold, Westerterp, K.R.   +2 more
core   +2 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Measurement of the axial gas dispersion coefficient in bubble columns of several diameters via gas flow modulation

This dataset was aquired during gas flow modualtion experiments for determining the axial gas dispersion coefficient in bubble columns. The applied measurement technique is gamma-ray densitometry and the dataset consists of densitometry measurements at ...
Schubert, Markus, Caggia, Vincenzo, Bieberle, André, Hampel, Uwe, Marchini, Sara   +4 more
core   +1 more source