Results 41 to 50 of about 1,963,356 (295)

Water Infusion on the Stability of Coal Specimen under Different Static Stress Conditions

open access: yesApplied Sciences, 2020
Underground coal mines are frequently subjected to water infusion, resulting in many mining hazards. This study investigated the effect of water infusion on the stress and energy evolution characteristics of coal specimens representing isolated pillars ...
Zilong Zhou, Lihai Tan, Xin Cai
doaj   +1 more source

Application of transfer function for quick estimation of gas flow parameters—A useful model‐based approach to enhancing measurements

open access: yesEngineering Reports, 2021
At the core of chemical engineering, process design is fundamental to reach a goal of productivity. Axial dispersion is one of the key phenomena that can affect productivity.
Mirosław K. Szukiewicz, Adrian Szałek
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Dynamic studies of nitrophenols sorption on perfil in a fixed-bed column

open access: yesMacedonian Journal of Chemistry and Chemical Engineering, 2008
The adsorption of two substituted nitrophenols, namely 4-nitrophenol (4-NP) and 2,4-dinitrophenol (2,4-DNP), from aqueous solutions onto perfil was studied using a fixed bed column.
Zvezdelina Yaneva   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Sensing Strategies for Determining the Axial Gas Dispersion Coefficient in Bubble Columns via Gas Flow Modulation Technique

open access: yes, 2023
The gas flow modulation technique (GFM) is a recently proposed approach for measuring the axial gas dispersion coefficient in bubble columns. It is based on a time-resolved measurement of the modulated gas holdup at different axial positions in the ...
Eckhard Schleicher (11569351)   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Measurement of Axial Dispersion Coefficient of the Continuous Phase in a Pulsed Disc and Doughnut Column Using Dispersion Model with Radiotracer Technique [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2016
High efficiency and low required area for the pulsed columns are interesting and useful especially in nuclear industries in spite of exposure and radiation protection requirements.
M Tabasi   +3 more
doaj  

Axial dispersion model in predictive mass transfer correlation for random pulsed packed column [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2015
The continuous phase volumetric overall mass transfer coefficient in a ceramic intalox saddle pulsed packed extraction column using axial dispersion model was studied for two different liquid-liquid systems containing water/acetone/toluene and ...
Teflanab R.   +3 more
doaj   +1 more source

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