Results 91 to 100 of about 885,795 (303)

Classical and numerical approaches to determining V-section band clamp axial stiffness [PDF]

, 2014
V-band clamp joints are used in a wide range of applications to connect circular flanges, for ducts, pipes and the turbocharger housing. Previous studies and research on V-bands are either purely empirical or analytical with limited applicability on the ...
Khodabakhshi, Goodarz, Barrans, Simon, Muller, Matthias, Khodabakhshi Goodarz, Barrans, Simon M., Muller Matthias, Barrans Simon M.   +6 more
core   +1 more source

AN EXPERIENCE IN SIMULATION: THE CASE OF A VARIABLE DISPLACEMENT AXIAL PISTON PUMP

Proceedings of the JFPS International Symposium on Fluid Power, 1999
The paper presents an analysis of the simulated behaviour of two displacement control systems of an axial piston pump for open circuits. To arrive at predictive analyses the non linear model of the unit and its displacement controls have been developed in the AMESiml environment. The model, at constant displacement values, has been fine tuned by direct
GILARDINO, Luca, MANCO', Salvatore, NERVEGNA, Nicola, VIOTTO F.   +3 more
openaire   +3 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cascade Observer-Based Disturbance Estimation and Suppression for the Suspended Rotor in Maglev Hydrogen Recirculation Pump

Energies
Magnetic bearing hydrogen recirculation pumps enable high-speed, wear-free operation but are sensitive to flow-induced disturbances. This study proposes a cascade-structured disturbance observer (CDOB) that fuses rotor displacement and bearing current ...
Shiqiang Zheng, Jun Liu, Jinxiang Zhou
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Performance characterisation of a new photo-microsensor based sensing head for displacement measurement [PDF]

, 2016
This paper presents a robust displacement sensor with nanometre-scale resolution over a micrometre range. It is composed of low cost commercially available slotted photo-microsensors (SPMs).
Potdar, Akshay Anand, Longstaff, Andrew P., Fletcher, Simon   +2 more
core   +1 more source

Displacement-affectedness: a moral economy lens to examine protracted displacement

Surface-level descriptions of humanitarian responses to protracted displacement often obfuscate displaced people’s agency and conceal the role and significance of the ‘host community’.
Rajith Lakshman (19284424), Michael Collyer (4343698), Tahir Zaman (4468276), Ceri Oeppen (21839969)   +3 more
core   +4 more sources

Traceable Calibration Method for Online Measurement System of Train Wheelset Profile Based on Neural Network

机车电传动, 2019
As one of the basic equipment for rail transit operation and maintenance in China, the online measurement system of train wheelset mainly measures the running state of train running parts, including wheelset profile, tread abrasion and axle temperature ...
Enquan FANG, Jie QIN, Lili GENG
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source