Results 71 to 80 of about 7,931,210 (255)

Alternate operating methods for improving the performance of a continuous stirred tank reactor [PDF]

open access: yes, 2006
The effect of the pumping direction of an axial flow impeller, the feeding rate and the number of feed inlets on the operation of a continuously-fed stirred tank has been studied using CFD.
Fletcher, David F.   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

COMPARATIVE ANALYSIS OF WEIGHT AND COST INDICATIONS OF INDUCTION MOTORS WITH CYLINDRICAL AND AXIAL AIR GAPS

open access: yesElectrical engineering & Electromechanics, 2015
Purpose. To find the analytical expressions of determining the optimum geometric dimensions by criteria of the weight minimum and the cost minimum of axial field squirrel-cage induction motors and to compare traditional and axial field motors ...
А.А. Stavinskii, О.О. Palchykov
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Three-Dimensional Analytical Model for an Axial-Field Magnetic Coupling

open access: yes, 2014
International audienceIn this paper, we propose an analytical method for modeling a permanent magnets axial-field magnetic coupling. The three-dimensional model takes into account the radial fringing effects of the coupler.
Mezani, Smail   +3 more
core   +1 more source

Magnetic field control over the axial character of Higgs modes in charge-density wave compounds

open access: yesNature Communications
Understanding how symmetry-breaking processes generate order out of disorder is among the most fundamental problems of nature. The scalar Higgs mode – a massive (quasi-) particle – is a key ingredient in these processes and emerges with the spontaneous ...
Dirk Wulferding   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Predetermination of Currents and Field in Short-Circuit Voltage Operation for an Axial-Flux Permanent Magnet Machine [PDF]

open access: yes, 2008
Risk of irreversible magnet demagnetization during short-circuit fault is analyzed in case of an axial-flux dual-rotor machine, using a three-dimensional finite-element method (3D-FEM).
LOCMENT, Fabrice   +3 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Open Axial Field Magnet (OAFM)

open access: yes, 1978
Open Axial Field Magnet at test assembly.

core  

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