Results 51 to 60 of about 3,633,189 (235)

Multi-Parameter Optimization Design of Axial-Flow Pump Based on Orthogonal Method

open access: yesEnergies, 2022
The axial-flow pump is a widely used piece of general machinery which consumes large amounts of energy. In this study, an axial-flow pump with the specific speed of 536 is firstly designed and experimentally measured; then, the orthogonal method is ...
Zhenxing Dai   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Study of a regenerative pump using numerical and experimental techniques [PDF]

open access: yes, 2009
Regenerative pumps are the subject of increased interest in industry as these pumps are low cost, low specific speed, compact and able to deliver high heads with stable performance characteristics.
Scanlon, T.J.   +4 more
core   +3 more sources

Numerical analysis of pressure fluctuation characteristics of axial flow pump device of edge pump unit in multi-unit pumping station

open access: yesAIP Advances
Asymmetric layout gate station projects are prevalent in gate station engineering. When multiple pump units operate within such projects, the inflow patterns of the pump devices at different stations exhibit significant variations.
Sihai Li   +5 more
doaj   +1 more source

Design Method for Low Specific Speed Axial Flow Pump for High-Speed Undersea Vehicles

open access: yes水下无人系统学报
For the axial flow pumps water-jet propulsion system of undersea vehicles, the high specific speed axial flow pump designed by the lift method fails to work under shallow water and high-speed conditions at present.
Ziruo ZHANG, Kai LUO, Kan QIN
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Numerical Simulation of Flow Field Formed in Water Pump-Sump [PDF]

open access: yes, 2008
Two fundamental types of flow problems besetting water intakes are swirling flow problems in the pump sump and sediment problems at entrance or within intakes.
BOIS, Gérard   +2 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

The importance of the knowledge of flow stream in water sump pump [PDF]

open access: yes, 2013
Numerous different experimental and numerical methods have been developed and are already improved in order to get rather good flow descriptions inside pump components. These calculations are generally realized assuming uniform and steady flow conditions,
SIMONET, Sophie   +3 more
core  

A CFD parametric study of geometrical variations on the pressure pulsations and performance characteristics of a centrifugal pump. [PDF]

open access: yes, 2009
Pressure pulsations may be troublesome during the operation and performance of centrifugal pumps. Such pressure pulsations have traditionally been investigated experimentally but numerical analysis techniques allow these effects to be explored. The multi-
Amaral Teixeira, Joao, Spence, R.
core   +1 more source

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