Biomechanics of porcine renal arteries and role of axial stretch. [PDF]
, 2013 International audienceIt is known that arteries experience significant axial stretches in vivo. Several authors have shown that the axial force needed to maintain an artery at its in vivo axial stretch does not change with transient cyclical ...
Avril, Stéphane +4 more
core +4 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Computer program to determine pressure distributions and forces on blunt bodies of revolution [PDF]
, 1973 Program was written to include integration of surface pressure in order to obtain axial-force, normal-force, and pitching-moment coefficients.
Jackson, C. M., Jr. +2 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Dual strain gage balance system for measuring light loads [PDF]
, 1991 A dual strain gage balance system for measuring normal and axial forces and pitching moment of a metric airfoil model imparted by aerodynamic loads applied to the airfoil model during wind tunnel testing includes a pair of non-metric panels being rigidly
Roberts, Paul W.
core +1 more source
Free vibration of axially loaded thin-walled composite box beams [PDF]
, 2009 A general analytical model applicable to flexural–torsional coupled vibration of thin-walled composite box beams with arbitrary lay-ups under a constant axial force has been presented.
Banerjee +23 more
core +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Acoustic frequency spectrum characteristics in periodic drill string under tension
Energy Science & Engineering, 2020 It is a promising measure to transmit downhole information by acoustic wave through drill string. However, the transmission distance and quality of acoustic signals in field conditions are still not satisfied because the acoustic frequency spectrum in ...
Qing Wang, Zhichuan Guan, Yongwang Liu
doaj +1 more source
Design and experimental characterization of a tunable vibration-based electromagnetic micro-generator [PDF]
, 2010 Vibration-based micro-generators, as an alternative source of energy, have become increasingly significant in the last decade. This paper presents a new tunable electromagnetic vibration-based micro-generator.
Akoun +19 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source