Results 61 to 70 of about 3,113,878 (299)
Effect of Wind Loading Pattern on Shear Lag Phenomenon in Framed-Tube Building [PDF]
Journal of Rehabilitation in Civil EngineeringHigh-rise tubular buildings experience the shear lag phenomenon due to wind load. This phenomenon results in tension in upper storey columns that may adversely affect building stability.
Ashish Singh +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Ingeniería Mecánica, 1999 Durante el movimiento de un material en un transportador de sinfín surge una fuerza en dirección axial que influye en laselección de uno de los cojinetes de apoyo del equipo.
F. Aguilar Parés
doaj
Bolted circular flange connections under static bending moment and axial force
Journal of constructional steel research, 2019 The available design rules to evaluate the force distributions in the tension and the compression parts of bolted circular flange connections under bending moment and axial are often based on the beam theory which is not adequate.
M. Couchaux +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
工程科学与技术, 2021 To effectively evaluate the loss of axial force for the bolts in cable clamp of suspension bridge, the influence factors analyses and application of ultrasonic identification method for cable clamp blot axial force in suspension bridge were carried out ...
Xin CHEN +3 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Journal of Mechanical Engineering, 2021 This paper deals about experimental determination of changing the axial load in the bolts of the clamping sleeve under its axial load. Inspiration for this experiment was FEM analysis clamping sleeve in Ansys workbench.
Lukáš Hruzík +2 more
doaj +1 more source