Results 41 to 50 of about 99,325 (262)

Effect of Steel Support Cross-Section and Preloaded Axial Force on the Stability of Deep Foundation Pits

Buildings
To investigate the effects of steel support cross-section dimensions and preloaded axial force levels on the stability of foundation pits, numerical simulations were conducted for open-cut deep foundation pits based on monitoring data from Changchun ...
Yang Jin, Hanzhe Zhao, Chuanfeng Zheng, Jian Liu, Chong Ding   +4 more
doaj   +1 more source

Direct-Drive Conical-Rotor Permanent Magnet Synchronous Generator for Turbo-Expander, Accounting for Adaptive Equilibrium of Axial Force

IEEE Access, 2018
The permanent magnet synchronous generator (PMSG) has been widely employed in high-speed direct-drive turbo-expander for distributed energy generation.
Jiaobao Wang, Shoudao Huang, Chao Guo, Haokun Wu, Yaojing Feng   +4 more
doaj   +1 more source

Exact Stiffness Matrix for Nonprismatic Beams with Parabolic Varying Depth

Journal of Engineering, 2023
In this paper, an exact stiffness matrix and fixed-end load vector for nonprismatic beams having parabolic varying depth are derived. The principle of strain energy is used in the derivation of the stiffness matrix. The effect of both shear deformation
Musab Aied Qissab Al-Janabi
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Wear analysis of finger locks with different design parameters for landing gear

Science Progress, 2020
The finger lock in the retractable actuator of the landing gear will wear during repeated unlocking and locking. Therefore, the effects of six parameters including the material of the finger lock, the length of the finger lock, the diameter of the finger
Yu Hou, Ming Zhang, Hong Nie
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Effect of Wind Loading Pattern on Shear Lag Phenomenon in Framed-Tube Building [PDF]

Journal of Rehabilitation in Civil Engineering
High-rise tubular buildings experience the shear lag phenomenon due to wind load. This phenomenon results in tension in upper storey columns that may adversely affect building stability.
Ashish Singh, Piyush Gaikwad, Sasankasekhar Mandal   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source