Results 81 to 90 of about 2,616,986 (302)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Biomedical Sciences and Clinical MedicineOBJECTIVE To evaluate the correlation between chin-throat length and oropharyngeal volume, minimum axial area, and polysomnographic indices in patients undergoing orthodontic treatment.
Wachira Tantirittiporn +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Diabetes mellitus and the eye: axial length [PDF]
Background and aims: The refractive error of the eye is dependent on its axial length. Refractive error is known to fluctuate significantly in poorly controlled diabetic patients.
O’Donnell, C., Huntjens, B.
core +3 more sources
Ocular axial length changes following trauma: Blunt versus penetrating
TNOA Journal of Ophthalmic Science and Research, 2019 Aims: This study aims to analyze the effect of penetrating and blunt trauma on ocular axial length. Settings and Design: This is a retrospective study.
Madhu Shekhar +2 more
doaj +1 more source
Biomedicine Hub, 2020 Purpose: The aim of this study was to evaluate the foveal avascular zone (FAZ) of healthy subjects and examine the magnification effect. Methods: A total of 33 healthy volunteers were enrolled and all subjects were eligible for analysis.
Mika Suda +7 more
doaj +1 more source
The inverse correlation between RNFL thickness and axial length.
, 2018 The inverse correlation between RNFL thickness and axial length.
Pei-Chen Wu (141736) +8 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Axial length and mean retinal layer thickness measurements.
, 2018 Axial length and mean retinal layer thickness measurements.
Young Hoon Lee (1431625) +1 more
core +1 more source
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source