Results 81 to 90 of about 4,134,746 (302)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Refractive Results and Complications of Lensectomy in Simple Extreme Microphthalmos Cases

Türk Oftalmoloji Dergisi
Objectives: To evaluate the refractive outcomes, changes in intraocular pressure (IOP) and anterior chamber depth (ACD), and postoperative complications following lensectomy for angle-closure in cases of simple extreme microphthalmos.
Gülşah Gümüş Akgün, Neşe Alagöz, Ece Doğruel, Nilay Kandemir Beşek, Ahmet Kırgız, Erdem Erdoğdu, İhsan Çakır, Çiğdem Altan, Tekin Yaşar   +8 more
doaj   +1 more source

Axial Length Correction in Evaluation of Refractive Predictability and Biometry Agreement [Response to Letter]

Clinical Ophthalmology, 2023
Bjørn Gjerdrum,1 Kjell Gunnar Gundersen,1 Christian Nilsen,1,2 Morten Gundersen,1,2 Per Jensen1,2 1Ifocus Eye Clinic, Stavanger, Norway; 2Faculty of Health Sciences, Oslo Metropolitan University, Oslo, NorwayCorrespondence: Bjørn Gjerdrum ...
Gjerdrum B, Gundersen KG, Nilsen C, Gundersen MM, Jensen P   +4 more
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Does Chin-Throat Length Relate to Oropharyngeal Volume, Minimum Axial Area, and Polysomnographic Indices?

Biomedical Sciences and Clinical Medicine
OBJECTIVE To evaluate the correlation between chin-throat length and oropharyngeal volume, minimum axial area, and polysomnographic indices in patients undergoing orthodontic treatment.
Wachira Tantirittiporn, Nuntigar Sonsuwan, Warit Powcharoen, Dhirawat Jotikasthira, Thanapat Sastraruji, Pathaweex Pathawee Khongkhunthian, Kachaphol Kuharattanachai, Kanich Tripuwabhrut   +7 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Ocular axial length changes following trauma: Blunt versus penetrating

TNOA Journal of Ophthalmic Science and Research, 2019
Aims: This study aims to analyze the effect of penetrating and blunt trauma on ocular axial length. Settings and Design: This is a retrospective study.
Madhu Shekhar, Hemant Sonawane, Haripriya Aravind   +2 more
doaj   +1 more source

Magnification Effect of Foveal Avascular Zone Measurement Using Optical Coherence Tomography Angiography

Biomedicine Hub, 2020
Purpose: The aim of this study was to evaluate the foveal avascular zone (FAZ) of healthy subjects and examine the magnification effect. Methods: A total of 33 healthy volunteers were enrolled and all subjects were eligible for analysis.
Mika Suda, Yuji Yoshikawa, Gaku Terauchi, Soiti Matsumoto, Takuhei Shoji, Kei Shinoda, Atsushi Mizota, Yoshiharu Kobayashi   +7 more
doaj   +1 more source

Optical ‘dampening’ of the refractive error to axial length ratio: implications for outcome measures in myopia control studies

Ophthalmic & physiological optics, 2018
To gauge the extent to which differences in the refractive error axial length relationship predicted by geometrical optics are observed in actual refractive/biometric data.
Fiona E Cruickshank, N. Logan
semanticscholar   +1 more source