Results 71 to 80 of about 1,606,706 (292)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Research on Mechanical Shim Application with Compensated Prompt γ Current of Vanadium Detectors
Nuclear Engineering and Technology, 2017 Mechanical shim is an advanced technology for reactor power and axial offset control with control rod assemblies. To address the adverse accuracy impact on the ex-core power range neutron flux measurements-based axial offset control resulting from the ...
Zhi Xu
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Axial field permanent magnet DC motor with powder iron armature
, 2007 The paper describes a double-gap axial field permanent magnet (PM) dc motor whose double-layer armature wave winding is constructed of copper strips.
Mohammad, Mohammad T. +1 more
core +1 more source
Predicting The Axial Load Of Capacity Of Joints Formed By V-Band Retainers [PDF]
V-band retainers are widely used in the automotive, aircraft and aerospace industries to connect a pair of circular flanges to provide a joint with good axial strength and torsional rigidity.
Blunt, Liam, Müller, M.
core +4 more sources
Investigation of Offset Recovery Algorithms for High-Performance Bluetooth Receivers
, 2005 Research has shown that significant degradation in performance can occur even when operating within the limits for carrier frequency and modulation index offsets permitted by the Bluetooth standard.
Tibenderana, C +3 more
core +1 more source
Ultimate axial load capacity of v-band clamp joints. [PDF]
, 2009 Band clamps with a flat bottomed V-section are used to connect a pair of circular flanges to provide a joint with significant axial strength. Despite the wide application of V-band clamps, their behaviour is not fully understood and the ultimate axial ...
Barrans, Simon, Muller, M
core +3 more sources
IEEE Access, 2020 In order to improve poor anti-offset capability of rotary transformer in electric excitation motor, a coaxial nested rotary wireless power transfer (CNR-WPT) system has been proposed in this paper.
Longyang Wang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source