Results 81 to 90 of about 1,606,706 (292)

Vibration and buckling of thin-walled composite I-beams with arbitrary lay-ups under axial loads and end moments [PDF]

open access: yes, 2013
A finite element model with seven degrees of freedom per node is developed to study vibration and buckling of thin-walled composite I-beams with arbitrary lay-ups under constant axial loads and equal end moments.
Lee, Jaehong, Vo, Thuc
core   +1 more source

Experimental Study of Laterally Offset RHS X-Connections in Branch Axial Tension [PDF]

open access: yes, 2023
In all predominant design guides for truss-type welded Rectangular Hollow Section (RHS) connections, the branch and chord member axes are assumed to lie in the same plane.
Davidian, Vartkes
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Low-complexity high-performance GFSK receiver with carrier frequency offset correction [PDF]

open access: yes, 2004
This paper presents an implementation of a GFSK receiver based on matched filtering of a sequence of K successive bits. This enables improved detection and superior BER performance but requires 2K matched filters of considerable complexity.
Weiss, Stephan   +5 more
core   +1 more source

Performance Characteristics of a New Generation 148-cm Axial Field-of-View uMI Panorama GS PET/CT System with Extended NEMA NU 2-2018 and EARL Standards

open access: yesJournal of Nuclear Medicine
Visual Abstract The uMI Panorama GS PET/CT system is a new long-axial-field-of-view scanner featuring high sensitivity, time-of-flight (TOF) resolution, spatial resolution, and count rate performance.
Hai-Qiong Zhang   +7 more
semanticscholar   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Experimental comparison between a counter-rotating axial-flow fan and a conventional rotor-stator stage [PDF]

open access: yes, 2013
Based on the requirement of energy consumption level and weight and dimension restriction, compact axial machines are highly demanded in many industrial fields.
BAKIR, Farid   +2 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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