Results 141 to 150 of about 1,034,274 (259)

Clinical Phenotypes, Treatment, and Outcomes of Rheumatic Immune–Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitors: A Rheumatologists‐Referred Multicenter German Registry Cohort

ACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective Immune checkpoint inhibitors (ICIs) induce a broad range of immune‐related adverse events (irAEs), including rheumatic manifestations. Evidence from dedicated rheumatology cohorts on the clinical spectrum, severity, treatment, and outcomes of rheumatic irAEs (rh‐irAEs) remains limited.
Didzis Gailis, Fabian T.H. Ullrich, Sophia Dombret, Marc Schmalzing, Rebecca Hasseli‐Fräbel, Torsten Witte, Thea Thiele, Uta Kiltz, Mara Oleszowsky, Marcel Müller, Karolina Gente, Christof Specker, Matthias B. Thaler, Alla Skapenko, Hendrik Schulze‐Koops   +14 more
wiley   +1 more source

IgG Glycosylation Patterns May Identify Distinct Clinical Trajectories in Fibromyalgia Patients: A Longitudinal Pilot Study

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Altered immunoglobulin G (IgG) glycosylation was implicated in various conditions, but its role in fibromyalgia (FM) remains unclear. This study investigated IgG glycosylation patterns in FM patients and associations between glycosylation changes and clinical profiles.
Ling‐Cheng Kung, Nguyen Thanh Nhu, Yu‐Ying Yu, I‐Lin Tsai, Jiunn‐Horng Kang   +4 more
wiley   +1 more source

Combination Treatment of IL‐17 Inhibitor and JAK Inhibitor in Psoriatic Arthritis: A Case Report and Scoping Review

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Background Psoriatic arthritis (PsA) is a chronic inflammatory disease with complex pathophysiology. Despite advancements in biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs), treatment responses remain suboptimal for many patients.
Mengduan Pang, Ling Li, Qi Zhang, Min Zhao   +3 more
wiley   +1 more source

Hematological Inflammation Indices Are Associated With Active Uveitis in Ankylosing Spondylitis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
Hematological inflammation indices reflect the systemic inflammatory burden in ankylosing spondylitis. Patients with active uveitis exhibit a distinct pro‐inflammatory profile characterised by increased NLR, PLR, SII, SIRI, and AISI, along with decreased HALP and CALLY scores.
Mesude Seda Aydoğdu, Zarife Ekici Gök
wiley   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Sex, Sex Hormones and Inflammatory Burden and Cardiovascular Risk in Patients with Spondyloarthritis

Biomolecules
Spondyloarthritis encompasses a spectrum of inflammatory diseases, including axial spondyloarthritis and peripheral forms such as psoriatic arthritis.
Isaac T. Cheng, Huan Meng, Ho So, Lai Shan Tam   +3 more
doaj   +1 more source

The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection

Annals of the Rheumatic Diseases, 2009
M. Rudwaleit, D. M. van der Heijde, R. Landewé, J. Listing, N. Akkoç, J. Brandt, Jürgen Braun, C.-T. Chou, E. Collantes-Estévez, M. Dougados, Feng Huang, Jie-Ruo Gu, M. Khan, Y. Kirazlı, W. Maksymowych, H. Mielants, I. Sørensen, S. Ozgoçmen, E. Roussou, R. Valle-Oñate, U. Weber, J. Wei, J. Sieper   +22 more
semanticscholar   +1 more source

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa, Martin Pezous, David Klatzmann, Encarnita Mariotti‐Ferrandiz   +3 more
wiley   +1 more source

Similarities and differences: disentangling the intersection between axial psoriatic arthritis and axial spondyloarthritis

Therapeutic Advances in Musculoskeletal Disease
Spondyloarthritis is a group of chronic inflammatory diseases that includes axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). AxSpA primarily affects the axial skeleton, manifesting with hallmark features such as inflammatory back pain and a
Murat Torgutalp, Henriette Käding, Fabian Proft   +2 more
doaj   +1 more source

Higher body mass index and anti-drug antibodies predict the discontinuation of anti-TNF agents in Korean patients with axial spondyloarthritis

Revista Brasileira de Reumatologia
Objective: The development of anti-drug antibodies against tumor necrosis factor inhibitors is a likely explanation for the failure of TNF-inhibitors in patients with spondyloarthritis.
Jiwon Hwang, Hye-Mi Kim, Hyemin Jeong, Jaejoon Lee, Joong Kyong Ahn, Eun-Mi Koh, Eun-Suk Kang, Hoon-Suk Cha   +7 more
doaj   +1 more source