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Axial spondyloarthritis.

The Lancet
Axial spondyloarthritis manifests as a chronic inflammatory disease primarily affecting the sacroiliac joints and spine. Although chronic back pain and spinal stiffness are typical initial symptoms, peripheral (ie, enthesitis, arthritis, and dactylitis ...
V. Navarro-Compán, A. Sepriano, D. Capelusnik, Xenofon Baraliakos   +3 more
semanticscholar   +11 more sources

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Axial Spondyloarthritis: A Review.

JAMA
Importance Axial spondyloarthritis is an immune-mediated inflammatory condition involving the sacroiliac joints, spine, and peripheral joints. It affects approximately 1% of adults in the US and is associated with impaired physical function and reduced ...
M. Bittar, A. Deodhar
semanticscholar   +3 more sources

Novel therapies in axial spondyloarthritis

Best Practice & Research Clinical Rheumatology, 2022
Over the past two decades, advancements in understanding the pathogenesis of axial spondyloarthritis have led to discoveries of new therapeutic targets, particularly the interleukin-17, tumor necrosis factor axis, and Janus kinase-signal transducer and activator of transcription pathway.
Mohamad, Bittar, Philip, Mease
core   +4 more sources

Axial Spondyloarthritis in Japan

Current Rheumatology Reports, 2022
The differences in the epidemiology and management of patients with axial spondyloarthritis (axSpA) among regions and countries largely depend on the positivity of human leukocyte antigen (HLA)-B27 and the health care system. This review article focused on axSpA in Japan, where the prevalence of HLA-B27 is extremely low (0.3%) and the universal health ...
Hideto Kameda, Mitsumasa Kishimoto, Shigeto Kobayashi, Tetsuya Tomita, Akimichi Morita, Masahiro Yamamura   +5 more
openaire   +2 more sources

Treatment of Axial Spondyloarthritis: What Does the Future Hold? [PDF]

Current Rheumatology Reports, 2020
Purpose of Review: To provide a summary of the recent and expected developments related to the treatment of axial spondyloarthritis. Recent Findings: An increasing number of interleukin-17 blocking agents show efficacy in axial spondyloarthritis ...
Denis Poddubnyy, Joachim Sieper
exaly   +2 more sources

Axial spondyloarthritis

The Lancet, 2013
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease predominantly of the sacroiliac joint (SIJ) and the spine. It starts normally in the second decade of life and has a slight male predominance. The prevalence is between 0.2% and 0.8% and is strongly dependent on the prevalence of HLA-B27 in a given population.
Joachim, Sieper, Denis, Poddubnyy
openaire   +2 more sources

Axial Spondyloarthritis

, 2019
From the Publisher: Focusing on the key essentials you need to know, Axial Spondyloarthritis provides a quick, expert overview of axSpA from a clinical perspective. This concise resource by Drs.
Adam Berlinberg, Kristine A. Kuhn
core   +3 more sources

Nonradiographic axial spondyloarthritis

Best Practice & Research Clinical Rheumatology, 2017
Non-radiographic axial spondyloarthritis (nr-axSpA) is a complex disease process that is part of the spectrum of axial spondyloarthritis (axSpA). This article reviews the current state of the literature as the understanding of this disease spectrum expands. The conceptual history and terminology, genetics, and epidemiology are reviewed.
Megan M, Lockwood, Lianne S, Gensler
openaire   +2 more sources

Mimics of axial spondyloarthritis

Current Opinion in Rheumatology, 2019
Purpose of reviewAxial spondyloarthritis (AxSpA) is a distinct clinical entity with characteristic clinical and radiographic features; however, a multitude of other metabolic, infectious and inflammatory disorders mimic it both clinically and radiographically.Recent findingsWe present in this review article recent updates about the various disease ...
Sali, Merjanah, Ann, Igoe, Marina, Magrey   +2 more
openaire   +2 more sources