Results 91 to 100 of about 2,434,328 (286)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Axial Spondyloarthritis

open access: yes, 2016
Axial spondyloarthritis is the commonest inflammatory arthritis affecting the spine. Typically first presenting to a variety of primary and secondary care professionals, the high global disease burden of this condition has created a need for increased ...

core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Axial and Radial Variation of Fibre Characteristics of Bambusa vulgaris

open access: yesJournal of Scientific Research and Reports, 2019
This study was carried out to investigate the axial and radial variations of fibre characteristics of Bambusa vulgaris. There were eighteen treatments for both axial and radial variations. The treatments were replicated three (3) times, in Complete Randomized Design (CRD).
E. A. Adelusi, A. F. Aderounmu
openaire   +2 more sources

Variation in aerodynamic coefficients with altitude

open access: yesResults in Physics, 2017
Precise aerodynamics performance prediction plays key role for a flying vehicle to get its mission completed within desired accuracy. Aerodynamic coefficients for same Mach number can be different at different altitude due to difference in Reynolds ...
Faiza Shahid   +3 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Numerical Investigation of Pressure Fluctuation Characteristics in a Centrifugal Pump with Variable Axial Clearance

open access: yesInternational Journal of Rotating Machinery, 2016
Clearance flows in the sidewall gaps of centrifugal pumps are unsteady as well as main flows in the volute casing and impeller, which may cause vibration and noise, and the corresponding pressure fluctuations are related to the axial clearance size.
Lei Cao   +3 more
doaj   +1 more source

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